Effect of Lidocaine on Reducing Injury in a Rat Electrical Burn Model

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dc.authoridOz Puyan, Fulya/0000-0001-5853-0109
dc.authoridPuyan, Fulya/0000-0001-5853-0109
dc.authorwosidOz Puyan, Fulya/A-7077-2018
dc.authorwosidPuyan, Fulya/V-7074-2019
dc.contributor.authorBenlier, Erol
dc.contributor.authorEskiocak, Sevgi
dc.contributor.authorPuyan, Fulya Oz
dc.contributor.authorSikar, Emel Yurdakul
dc.contributor.authorKandulu, Huseyin
dc.contributor.authorOmurlu, Imran Kurt
dc.contributor.authorTop, Husamettin
dc.date.accessioned2024-06-12T11:00:10Z
dc.date.available2024-06-12T11:00:10Z
dc.date.issued2012
dc.departmentTrakya Üniversitesien_US
dc.description6th Congress of the Balkan-Association-of-Plastic-Reconstructive-and-Aesthetic-Surgery -- JUN 04-07, 2009 -- Ohrid, MACEDONIAen_US
dc.description.abstractElectrical injuries induce progressive tissue loss. We evaluated the effect of lidocaine on tissue necrosis after electrical burn injuries. Forty-two male Wistar albino rats (250-300 g) were divided into 3 groups [Group A (n = 6), control group without an electrical burn injury; and Groups B (n = 18) and C (n = 18), electrical burn injury groups without and with lidocaine therapy, respectively]. Three separate analyses were performed at different time points on 6 of 18 rats from Groups B and C at each time point. Electrical burns were induced by applying 220 V AC between the left upper and right lower extremities for 10 seconds. Myeloperoxidase and malondialdehyde levels were measured in skin and muscle biopsy specimens after the first hour, fresh and dry weight differences in the amputated extremities were calculated after 24 hours, and live and necrotic tissue areas were measured at 7 days after burn injury. We found that lidocaine reduced edema, the number of neutrophils, and neutrophil damage in tissues. We conclude that lidocaine decreased the amount of necrotic tissue caused by electric injury.en_US
dc.description.sponsorshipBalkan Assoc Plast Reconstruct & Aesthet Surgen_US
dc.identifier.doi10.1097/SAP.0b013e3182586b2a
dc.identifier.endpage156en_US
dc.identifier.issn0148-7043
dc.identifier.issn1536-3708
dc.identifier.issue2en_US
dc.identifier.pmid22772068en_US
dc.identifier.scopus2-s2.0-84863983153en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage152en_US
dc.identifier.urihttps://doi.org/10.1097/SAP.0b013e3182586b2a
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20728
dc.identifier.volume69en_US
dc.identifier.wosWOS:000306559000005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnnals Of Plastic Surgeryen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectric Burnsen_US
dc.subjectLidocaineen_US
dc.subjectNeutrophilsen_US
dc.subjectMyeloperoxidaseen_US
dc.subjectRatsen_US
dc.subjectManagementen_US
dc.subjectDynamicsen_US
dc.titleEffect of Lidocaine on Reducing Injury in a Rat Electrical Burn Modelen_US
dc.typeConference Objecten_US

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