Caudal neostigmine for postoperative analgesia in paediatric surgery

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dc.contributor.authorMemis, D
dc.contributor.authorTuran, A
dc.contributor.authorKaramanlioglu, B
dc.contributor.authorKaya, G
dc.contributor.authorSüt, N
dc.contributor.authorPamukçu, Z
dc.date.accessioned2024-06-12T10:51:36Z
dc.date.available2024-06-12T10:51:36Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: This study was conducted to evaluate analgesia and side-effects of caudal neostigmine coadministered with bupivacaine in paediatric surgery. Methods: We studied children, aged 1-5 years, undergoing elective surgery (inguinal hernia and hypospadias). After standard induction of anaesthesia, caudal anaesthesia was performed. Group 1 received 0.25% bupivacaine 0.5 ml.kg(-1) and Group 2 received 0.25% bupivacaine 0.5 ml.kg(-1) with 1 mug.kg(-1) neostigmine via the caudal route. Heart rate, mean arterial pressure, peripheral oxygen saturation were recorded before induction, after induction but before caudal anaesthesia, and then every 5 min after caudal anaesthesia. Haemodynamic, Toddler, Preschooler, Postoperative Pain Scale (TPPPS) pain score and sedation score values were recorded 30 min after extubation and at hours 2, 4, 6, 12 and 24. A pain score >3/10 resulted in administration of rectal paracetamol. The duration of postoperative analgesia was defined as the time between caudal drug injection and the first rectal paracetamol administration. Results: There were no differences between the groups in demographic and haemodynamic date, duration of surgery and anaesthesia, time to extubation or sedation scores. The duration of postoperative pain relief did not differ between the two groups; 15.40 +/- 10.97 h for group 1 vs. 15.45 +/- 10.99 h for group 2 (P > 0.05). The incidence of nausea (three patients in group 2 and one patient in group 1) was not statistically significant. No other side-effects were seen. Conclusions: We found that a single caudal injection of 1 mug.kg(-1) neostigmine mixed with bupivacaine offers no significant advantage over bupivacaine alone for postoperative pain relief in children undergoing genitourinary surgery.en_US
dc.identifier.doi10.1046/j.1460-9592.2003.01020.x
dc.identifier.endpage328en_US
dc.identifier.issn1155-5645
dc.identifier.issue4en_US
dc.identifier.pmid12753445en_US
dc.identifier.scopus2-s2.0-0038729605en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.1046/j.1460-9592.2003.01020.x
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18407
dc.identifier.volume13en_US
dc.identifier.wosWOS:000182784000007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBlackwell Publishing Ltden_US
dc.relation.ispartofPaediatric Anaesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnalgesiaen_US
dc.subjectPaediatricen_US
dc.subjectTechniquesen_US
dc.subjectCaudalen_US
dc.subjectBupivacaineen_US
dc.subjectAnticholinesteraseen_US
dc.subjectNeostigmineen_US
dc.subjectPainen_US
dc.subjectPostoperativeen_US
dc.subjectNucleus Raphe Magnusen_US
dc.subjectEpidural Neostigmineen_US
dc.subjectPediatric-Surgeryen_US
dc.subjectChildrenen_US
dc.subjectBupivacaineen_US
dc.subjectMorphineen_US
dc.subjectAnesthesiaen_US
dc.subjectClonidineen_US
dc.subjectLidocaineen_US
dc.subjectKetamineen_US
dc.titleCaudal neostigmine for postoperative analgesia in paediatric surgeryen_US
dc.typeArticleen_US

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