Maternal-fetal outcomes of pregnancies with thrombocytopenia-one center experience

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dc.authorscopusid57203575448
dc.authorscopusid57200002500
dc.authorscopusid35606878500
dc.authorscopusid57193905969
dc.authorscopusid6603020540
dc.contributor.authorYener C.
dc.contributor.authorAtes S.
dc.contributor.authorSayin C.
dc.contributor.authorSütcü H.
dc.contributor.authorVarol F.
dc.date.accessioned2024-06-12T10:26:33Z
dc.date.available2024-06-12T10:26:33Z
dc.date.issued2019
dc.description.abstractObjective: To investigate the etiology, obstetric risk factors, complications, and outcomes of pregnancies affected by thrombocytopenia. Material and Methods: A retrospective surveillance study was conducted based on the hospital records of 1286 women that gave birth during the period between 1st January 2017 and 31st December 2018 at the Department of Gynecology and Obstetrics of the Trakya University's School of Medicine. Clinical data including basic history, physical examination, and investigations of women with thrombocytopenia were evaluated. We randomly selected 154 patients without thrombocytopenia that delivered in our clinic during the same period, as the control group, and compared the maternal and fetal outcomes with the thrombocytopenic patient group. Results: A total of 154 out of 1286 women (11.9%) had thrombocytopenia of varying severity. Gestational thrombocytopenia (GT) was the most common cause, being identified in 76.2% of the cases with thrombocytopenia. This was followed by preeclampsia (15.5%). About 4.5% of pregnant women with thrombocytopenia were accounted for by idiopathic thrombocytopenic purpura (ITP), 2.5% of the patients by eclampsia, while HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome was observed in 1.3% of the pregnant women with thrombocytopenia. An increased rate of IUGR (Intrauterine growth restriction), fetal distress, and adverse neonatal outcomes were recorded among patients that had thrombocytopenia with preeclampsia, eclampsia, and HELLP syndrome. Furthermore, we observed higher rates of fetal distress and adverse neonatal outcomes in patients with thrombocytopenia compared to the control group. Conclusion: GT was the most common cause of thrombocytopenia in pregnancy, followed by preeclampsia. Eclampsia, HELLP syndrome, and ITP were rare causes of this disorder during pregnancy. Early detection and treatment of expected complications are critical for the effective management of such cases. Copyright © 2019 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/jcog.2019-70169
dc.identifier.endpage99en_US
dc.identifier.issn2619-9467
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85095704772en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage94en_US
dc.identifier.trdizinid334171en_US
dc.identifier.urihttps://doi.org/10.5336/jcog.2019-70169
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/334171
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16876
dc.identifier.volume29en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherOrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.en_US
dc.relation.ispartofJournal of Clinical Obstetrics and Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGestational Thrombocytopenia; Hellp; Preeclampsia; Pregnancy; Thrombocytopeniaen_US
dc.subjectFresh Frozen Plasma; Adult; Adverse Outcome; Anemia; Apheresis; Article; Blood Transfusion; Case Control Study; Childbirth; Clinical Evaluation; Comparative Study; Controlled Study; Diabetes Mellitus; Disease Severity; Eclampsia; Female; Fetus; Fetus Death; Fetus Distress; Fetus Outcome; Gestational Thrombocytopenia; Hellp Syndrome; High Risk Pregnancy; Human; Hydramnios; Idiopathic Thrombocytopenic Purpura; Intrauterine Growth Retardation; Major Clinical Study; Medical History; Medical Record Review; Oligohydramnios; Physical Examination; Platelet Apheresis; Preeclampsia; Pregnancy; Pregnancy Complication; Pregnancy Diabetes Mellitus; Pregnancy Outcome; Pregnant Woman; Prevalence; Retrospective Study; Risk Factor; Solutio Placentae; Thrombocytopeniaen_US
dc.titleMaternal-fetal outcomes of pregnancies with thrombocytopenia-one center experienceen_US
dc.typeArticleen_US

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