Clinical features of the patient with multiple primary tumors: Single center experience

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dc.authoridHacioglu, Bekir/0000-0001-8490-3239
dc.authoridKöstek, Osman/0000-0002-1901-5603
dc.authoridHacıbekiroğlu, İlhan/0000-0002-0333-7405
dc.authoridCicin, Irfan/0000-0002-7584-3868
dc.authoridGökyer, Ali/0000-0002-1653-6155
dc.authorwosidHacioglu, Bekir/GZH-1824-2022
dc.authorwosidKöstek, Osman/AAA-3604-2019
dc.authorwosidErdogan, Bulent/AAA-9781-2021
dc.authorwosidHacıbekiroğlu, İlhan/JCN-7264-2023
dc.authorwosidCicin, Irfan/AAQ-5575-2020
dc.authorwosidGökyer, Ali/AAQ-5700-2020
dc.contributor.authorGokyer, Ali
dc.contributor.authorKostek, Osman
dc.contributor.authorHacioglu, Muhammet Bekir
dc.contributor.authorErdogan, Bulent
dc.contributor.authorKodaz, Hilmi
dc.contributor.authorTurkmen, Esma
dc.contributor.authorHacibekiroglu, Ilhan
dc.date.accessioned2024-06-12T11:08:23Z
dc.date.available2024-06-12T11:08:23Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractOBJECTIVE: Multiple primary tumors are the ones that develop in the same patient at the same or different times. They are usually examined under two groups. If the second tumor is diagnosed 6 months after the first tumor is diagnosed, it is named as metachronous tumor. If it is diagnosed in 6 months after the first diagnosis, it is called as synchronous tumor. The malignancy of tumors should be proved histologically. At least 2 cm of solid tissue should be present between two tumors. If they are at localized at the same place, a gap of at least 5 years should be present between them. Metastatic disease should be eliminated. This study aimedto review the clinical, demographic, and pathological features of multiple primary tumors, detect the prevalence, compare the results with literature findings, and evaluate and improve the approach to multiple primary tumors. METHODS: A total of 170 patients diagnosed with multiple primary tumors were included in this study. Patient data were obtained from pathology and medical reports of the patients. RESULTS: Most of the multiple primary tumors were metachronous. The number of male patients was more than that of female patients. The median time between double tumors was 3 monthsforsynchronous tumorsand 26 months for metachronous tumors. Synchronous tumors with the highest prevalence of comorbidity were lung-larynx and lung-colon, whereas metachronous tumors with the highest prevalence of comorbidity were lung-bladder, lung-larynx, breast-endometrium, and breast-colon. The history of smoking and alcohol was found to be higher in male patients andsynchronous tumors. CONCLUSION: The detection of the first tumor in the metastatic stage and an accompanying synchronous secondary tumor was found to be a poor prognostic factor. The treatment of the first tumor, smoking, squamous cell histology, and male gender were among the other factors negatively affecting survival, although they were not statistically significant.en_US
dc.identifier.doi10.14744/nci.2017.67044
dc.identifier.endpage51en_US
dc.identifier.issn2148-4902
dc.identifier.issue1en_US
dc.identifier.pmid28752142en_US
dc.identifier.startpage43en_US
dc.identifier.trdizinid241684en_US
dc.identifier.urihttps://doi.org/10.14744/nci.2017.67044
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/241684
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22405
dc.identifier.volume4en_US
dc.identifier.wosWOS:000408984000007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKare Publen_US
dc.relation.ispartofNorthern Clinics Of Istanbulen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMetachronousen_US
dc.subjectMultiple Primary Tumorsen_US
dc.subjectSurvivalen_US
dc.subjectSynchronousen_US
dc.subjectPrimary Malignanciesen_US
dc.subjectPrimary Neoplasmsen_US
dc.subjectPrimary Cancersen_US
dc.subjectInstitutionen_US
dc.subjectTobaccoen_US
dc.titleClinical features of the patient with multiple primary tumors: Single center experienceen_US
dc.typeArticleen_US

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