Antioxidant, anticholinesterase and antibacterial activities of jurinea consanguinea dc
Küçük Resim Yok
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of this study was to investigate in vitro antioxidant, anticholinesterase and antibacterial activities of the petroleum ether, chloroform and methanol extracts obtained from the aerial parts of Jurinea consanguinea DC. (Asteraceae). Total phenolic and flavonoid contents of these crude extracts were determined as pyrocatechol and quercetin equivalents, respectively. The methanol extract which possessed almost the same effect with the chloroform extract in ?-carotene-linoleic acid system exhibited higher free radical scavenging activity than a standard compound, BHT, at 100 and 200 ?/mL concentrations. The petroleum ether extract showed the highest acetylcholinesterase inhibitory activity among the tested extracts. The methanol extract exhibited higher butyrylcholinesterase inhibitory activity than galantamine at all concentrations (94% inhibition at 200 ?g/mL). The antibacterial activity of the extracts was determined by the disc diffusion method. The chloroform extract showed moderate activity against B. subtilis, P. aeruginosa and S. aureus. © 2011 Reproduction is free for scientific studies.
Açıklama
Anahtar Kelimeler
Antibacterial; Anticholinesterase; Antioxidant; Asteraceae; Jurinea Consanguinea, Acetylcholinesterase; Alpha Tocopherol; Antiinfective Agent; Antioxidant; Butylcresol; Catechol; Chloroform; Cholinesterase; Cholinesterase Inhibitor; Galantamine; Jurinea Consanguinea Extract; Methanol; Ofloxacin; Petroleum Ether; Plant Extract; Quercetin; Unclassified Drug; Antibacterial Activity; Antioxidant Activity; Article; Bacillus Subtilis; Cholinesterase Inhibition; Concentration Response; Controlled Study; Disk Diffusion; Drug Determination; Drug Mechanism; In Vitro Study; Jurinea Consanguinea; Klebsiella Pneumoniae; Medicinal Plant; Proteus Vulgaris; Pseudomonas Aeruginosa; Staphylococcus Aureus; Asteraceae; Jurinea; Staphylococcus Aureus
Kaynak
Records of Natural Products
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
5
Sayı
1
