Renal angiomyolipoma with malignant transformation, simultaneous occurrence with malignity and other complex clinical situations

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dc.authoridYALCIN, OMER TARIK/0000-0001-5626-1881
dc.authorwosidKaplan, Mustafa/D-4977-2014
dc.authorwosidYALCIN, OMER TARIK/B-4744-2018
dc.contributor.authorInci, Osman
dc.contributor.authorKaplan, Mustafa
dc.contributor.authorYalcin, Omer
dc.contributor.authorAtakan, Irfan Huseyin
dc.contributor.authorKubat, Huseyin
dc.date.accessioned2024-06-12T11:08:02Z
dc.date.available2024-06-12T11:08:02Z
dc.date.issued2006
dc.departmentTrakya Üniversitesien_US
dc.description.abstractRenal angiomyolipoma is a benign kidney tumor, which is characterized by the presence of mature or immature fat tissue, thick-walled blood vessels, and smooth muscles. However, there is a rare possibility of transformation to a malignancy. This transformation could be toward sarcoma. And also angiomyolipoma could be associated with renal adenocarcinorna in the same kidney. The aim of this study is to show the association of angiomyolipoma with complex clinical situations such as malign transformation, simultaneous occurrence with adenocarcinoma, bilateral tumors with tuberous sclerosis or Wunderlich Syndrome. Findings of clinical presentation, pathological evaluation, urography, ultrasonography, and computerized tomography of 19 patients who were diagnosed angiomyolipoma in our clinic during 1994-2003 were examined retrospectively. Our records indicated that radical nephrectomy was performed in three cases of angiomyolipoma in which the differential diagnosis from adenocarcinorna could not be made and in another case of angiomyolipoma, which was associated with adenocarcinoma. Simple nephrectomy was performed in four symptomatic angiomyolipoma cases with tumor size larger than 4 cm and partial nephrectomy in another case. In one case, renal angiomyolipoma was associated with adenocarcinoma in the same kidney. In one case, post-operative recurrence of angiomyolipoma developed 7 months after nephrectomy. This patient was diagnosed low-grade leiomyosarcoma. Angiomyolipoma is regarded as a benign tumor of the kidney; however, it may also show aggressive behaviors and rarely transform to sarcoma. It may also exist in the same kidney along with adenocarcinorna or sarcoma.en_US
dc.identifier.doi10.1007/s11255-005-4756-2
dc.identifier.endpage426en_US
dc.identifier.issn0301-1623
dc.identifier.issue3-4en_US
dc.identifier.pmid17033887en_US
dc.identifier.scopus2-s2.0-33847357798en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage417en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-005-4756-2
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22281
dc.identifier.volume38en_US
dc.identifier.wosWOS:000245215800005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology And Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMalignancyen_US
dc.subjectRenal Angiomyolipomaen_US
dc.subjectSarcomaen_US
dc.subjectTuberous Sclerosisen_US
dc.subjectTumoren_US
dc.subjectTuberous Sclerosisen_US
dc.subjectKidneyen_US
dc.subjectManagementen_US
dc.subjectCarcinomaen_US
dc.titleRenal angiomyolipoma with malignant transformation, simultaneous occurrence with malignity and other complex clinical situationsen_US
dc.typeArticleen_US

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