The effect of enamel matrix derivatives on root coverage: a 12-month follow-up of a randomized clinical trial

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dc.authoridErtugrul, Abdullah Seckin/0000-0002-9973-3161
dc.authoridSahin Aydinyurt, Hacer/0000-0002-9521-9704
dc.contributor.authorAydinyurt, Hacer Sahin
dc.contributor.authorTekin, Yasin
dc.contributor.authorErtugrul, Abdullah Seckin
dc.date.accessioned2024-06-12T11:02:38Z
dc.date.available2024-06-12T11:02:38Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractSubepithelial connective tissue grafts (SCTGs) with a coronally advanced flap (CAF) are accepted as the gold standard for covering denuded root surfaces. In recent years, enamel matrix derivatives (EMDs) have been used for their regenerative potential in periodontics. The aim of this split-mouth and randomized controlled study was to assess the clinical and aesthetical impacts of EMD application in combination with SCTG+CAF in patients with Miller's Class I and II gingival recessions in contralateral canines of the maxilla. Participants who underwent SCTG+CAF+EMD application were identified as the test group (n = 19) and those who underwent SCTG+CAF as control group (n = 19). The outcome parameters were recession depth/width, root coverage percentage, and root coverage aesthetic score (RES). RES was evaluated by two calibrated blind periodontists one year after the treatment. Statistically significant root coverage percentage was observed at one year post-treatment for both groups (p < 0.05). However, significant differences between the groups were not observed in terms of total RES and complete root coverage rate (p > 0.05). The test group had significantly better results than the control according to the soft tissue texture and mucogingival junction alignment results (p < 0.05). These results indicate that EMDs contribute to the healing of soft tissue without scarring. As a result of better wound healing, the EMD-added group exhibited better results in terms of the harmony of the mucogingival junction between adjacent teeth. This paper is the first split-mouth study in which SCTG+CAF and SCTG+CAF+EMD were compared using RES in bilateral canines.en_US
dc.description.sponsorshipUniversity of Van Yuzuncu Yil University (Committee of Research) [2014-SBE-D017]; Faculty of Dentistry at Van Yuzuncu Yil Universityen_US
dc.description.sponsorshipThis study was approved by Clinicaltrials.gov. Protocol registration and result system system (NCT03197610). This study was self-funded by the authors and by the University of Van Yuzuncu Yil University (Committee of Research 2014-SBE-D017). The authors thank the Faculty of Dentistry at Van Yuzuncu Yil University for its support.en_US
dc.identifier.doi10.1590/1807-3107bor-2019.vol33.0006
dc.identifier.issn1807-3107
dc.identifier.pmid30758406en_US
dc.identifier.scopus2-s2.0-85061490705en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.1590/1807-3107bor-2019.vol33.0006
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21365
dc.identifier.volume33en_US
dc.identifier.wosWOS:000468340500006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSociedade Brasileira De Pesquisa Odontologicaen_US
dc.relation.ispartofBrazilian Oral Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGingival Recessionen_US
dc.subjectAutrograftsen_US
dc.subjectPeriodonticsen_US
dc.subjectConnective-Tissue Graften_US
dc.subjectCoronally Advanced Flapen_US
dc.subjectGingival Recessionen_US
dc.subjectPeriodontal Regenerationen_US
dc.subjectHistologic Evaluationen_US
dc.subjectTunnel Techniqueen_US
dc.titleThe effect of enamel matrix derivatives on root coverage: a 12-month follow-up of a randomized clinical trialen_US
dc.typeArticleen_US

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