Comparison of Myocardial Perfusion Scintigraphy and Coronary Angiography Results in Breast Cancer Patients Treated with Radiotherapy

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dc.authoridÖzkan, Uğur/0000-0002-7552-7654
dc.authoridGURDOGAN, Muhammet/0000-0001-5650-9066
dc.authorwosidÖzkan, Uğur/ACR-6091-2022
dc.contributor.authorOzkan, Ugur
dc.contributor.authorGurdogan, Muhammet
dc.date.accessioned2024-06-12T10:55:11Z
dc.date.available2024-06-12T10:55:11Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBreast cancer is the most common type of malignancy in women and radiotherapy (RT) is an important part of treatment. Although it reduces cancer recurrence, it has been shown to cause accerelerated athnerosclerosis. This study aimed to compare the results of myocardial perfusion scintigraphy (MPS) for ischemia investigation with coronary angiography (CAG) findings and to investigate the effect of RT on the development of coronary artery disease in breast cancer patients who underwent RT. The results of 660 patients were analyzed and compared with each other in terms of clinical, demographic, laboratory parameters and MPS results. The mean age was 57.5 years and all of them were female. When the groups were compared, the Gensini score and marking of the left anterior descending artery (LAD) area as ischemic area localization were found more, but angiographically, the rate of severe stenosis in the area indicated by MPS was found to be lower in the RT group (p < 0.001). While the sensitivity of MPS in the RT group was 67.5% and non-RT group was 88.5% (p < 0.001), the result of our study shows that the sensitivity of the MPS test is significantly lower in the patient group receiving RT.en_US
dc.identifier.doi10.3390/curroncol30050346
dc.identifier.endpage4585en_US
dc.identifier.issn1198-0052
dc.identifier.issn1718-7729
dc.identifier.issue5en_US
dc.identifier.pmid37232804en_US
dc.identifier.scopus2-s2.0-85160223248en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage4575en_US
dc.identifier.urihttps://doi.org/10.3390/curroncol30050346
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19326
dc.identifier.volume30en_US
dc.identifier.wosWOS:001020304400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofCurrent Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast Canceren_US
dc.subjectCardiotoxicityen_US
dc.subjectCardio-Oncologyen_US
dc.subjectCoronary Angiographyen_US
dc.subjectMyocardial Perfusion Scintigraphyen_US
dc.subjectRadiotherapyen_US
dc.subjectArtery-Diseaseen_US
dc.subjectRadiation-Therapyen_US
dc.subjectTl-201en_US
dc.subjectHearten_US
dc.subjectValidationen_US
dc.subjectPlanaren_US
dc.subjectDamageen_US
dc.subjectWomenen_US
dc.titleComparison of Myocardial Perfusion Scintigraphy and Coronary Angiography Results in Breast Cancer Patients Treated with Radiotherapyen_US
dc.typeArticleen_US

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