A Destroyer Immunologic Cause in Small Cell Lung Carcinoma: Ectopic Cushing's Syndrome
Küçük Resim Yok
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Ekin Tibbi Yayincilik Ltd Sti-Ekin Medical Publ
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Ectopic secretion of adrenocorticotropic hormone (ACTH) related Cushing's syndrome (CS) is more frequently observed than many other paraneoplastic syndromes in patients with small cell lung cancer. Suppression of the cellular immune system in these patients is severe problem for both patients and physicians. In addition, the chemotherapy has been caused to severity and higher rate of hematological toxicity. We present a case of small cell lung cancer having a very poor prognosis, with a compressed humoral and cellular immune system due to an ectopic secretion of ACTH related CS. We report a rare case of combined immunosuppression in a case with small cell lung cancer in this paper. In addition, in the light of this special case and literature, we suggest treatment strategies for small cell lung cancer patients with CS.
Açıklama
Anahtar Kelimeler
Cushing's Syndrome, Small Cell Lung Cancer, Immunosuppression, Opportunistic Infections, Cancer
Kaynak
Trakya Universitesi Tip Fakultesi Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
N/A
Cilt
27
Sayı
3
