THE ROLE OF LYMPHOSCINTIGRAPHY AND SENTINEL LYMPH NODE BIOPSY IN PATIENTS DIAGNOSED AS BREAST CANCER DURING PREGNANCY

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dc.contributor.authorSezer, Atakan
dc.contributor.authorGentilini, Oreste
dc.date.accessioned2024-06-12T10:55:14Z
dc.date.available2024-06-12T10:55:14Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBreast cancer is one of the most diagnosed malignancies during pregnancy. The prevalence of breast cancer associated with pregnancy is estimated at 1: 3,000 deliveries and predicted to increase permanently due to the trend to defer childbearing to older ages. Although breast cancer is generally diagnosed in advanced stage during pregnancy, the treatment modality should be as similar as possible with non pregnant women. In non-pregnant women with early stage invasive breast cancer, axillary lymph node status is the most important prognostic factor for determination of accurate adjuvant treatment. Axillary lymph node dissection is associated with significant morbidity and the sentinel lymph node biopsy is performed using blue dye or lympho-scintigraphy with a radiocolloid. Blue dyes are classified as pregnancy class C drugs and lympho-scintigraphy with a radiocolloid is generally used for the sentinel lymph node biopsy during pregnancy in patients diagnosed with breast cancer. Some technical information should be considered before performing lymphoscintigraphy on breast cancer patients during pregnancy. The lymphoscintigraphy should be performed on the same day of intervention. Sentinel lymph node biopsy can be performed within 2-3 h p.i. with 3-5 MBq of 99m Tc radiocolloid. Diligent perinatal diagnostic examinations should be done to exclude any congenital malformations before performing a lymphoscintigraphy during pregnancy. In conclusion, breast cancer diagnosed during pregnancy is a difficult matter for both the families and physicians but lymphoscintigraphy and sentinel lymph node biopsy may result in optimal treatment for the pregnant breast cancer patients.en_US
dc.identifier.endpage145en_US
dc.identifier.issn2149-1976
dc.identifier.issue2en_US
dc.identifier.startpage143en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19347
dc.identifier.volume7en_US
dc.identifier.wosWOS:000218545300014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofJournal Of Breast Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast Canceren_US
dc.subjectPregnancyen_US
dc.subjectLymphoscintigraphyen_US
dc.subjectSentinel Lymph Node Biopsyen_US
dc.titleTHE ROLE OF LYMPHOSCINTIGRAPHY AND SENTINEL LYMPH NODE BIOPSY IN PATIENTS DIAGNOSED AS BREAST CANCER DURING PREGNANCYen_US
dc.typeArticleen_US

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