The Results of Hemoglobinopathy Screening in Hatay, the Southern Part of Turkey

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dc.authorwosidKaral, Yasemin/A-6622-2018
dc.contributor.authorOktay, Gonul
dc.contributor.authorAcipayam, Can
dc.contributor.authorIlhan, Gul
dc.contributor.authorKaral, Yasemin
dc.contributor.authorSakalli, Gulten
dc.contributor.authorYilmazoglu, Nurullah
dc.contributor.authorBasun, Suna
dc.date.accessioned2024-06-12T11:03:06Z
dc.date.available2024-06-12T11:03:06Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: beta-Thalassemia and hemoglobinopathies are common genetic disorders in Turkey, Because of this reason, either anemic people or couples before marriage are investigated for hemoglobinopathies routinly. In this retrospective study, our aim was to determine the frequency of p-thalassemia and hemoglobinopathies in Hatay, which is located in the southern part of Turkey. Material and Method: In this study, data from 70226 individuals, admitted to Antakya State Hospital Hemoglobinopathy Center in Hatay, both for the reason of anemia and before marriage investigations, were evaluated between January 2006 and October 2012. The blood samples were collected into EDTA-containing tubes and hematological parameters were analyzed using a Sysmex XT-2000i Hematology Analyzer. High performance liquid chromatography technique was used to determine the type of hemoglobin. Results: The frequency of hemoglobinopaties were 5% beta-Thalassemia trait, 6,3% sickle cell trait, 12.9% alpha-thalassaeiria trait? and 4.2 Pb other abnormal hemoglobinopaties variants. We detected 49 cases with homozygot p-thalassaemia, 60 cases with homozygot haemoglobin 5, 33 cases with HbH disease (thalassaemia intermedia) among all. Discussion: The frequency of p-thalassemia trait and other haernoglobinopathies in Hatay is found to be quite high as compared with other provinces in Turkey.en_US
dc.identifier.doi10.4328/JCAM.2427
dc.identifier.endpage9en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84950140002en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage6en_US
dc.identifier.trdizinid209652en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.2427
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/209652
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21534
dc.identifier.volume7en_US
dc.identifier.wosWOS:000376566300002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherDerman Medical Publen_US
dc.relation.ispartofJournal Of Clinical And Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHemoglobinopathy Screeningen_US
dc.subjectB-Thalassemiaen_US
dc.subjectSickle Cell Anemiaen_US
dc.subjectSickle-Cell-Anemiaen_US
dc.subjectBeta-Thalassemia Traiten_US
dc.subjectPrenatal-Diagnosisen_US
dc.subjectUrban Areaen_US
dc.subjectPrevalenceen_US
dc.subjectPopulationen_US
dc.subjectProgramen_US
dc.titleThe Results of Hemoglobinopathy Screening in Hatay, the Southern Part of Turkeyen_US
dc.typeArticleen_US

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