Intravenous regional anesthesia using prilocaine and neostigmine

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dc.contributor.authorTuran, A
dc.contributor.authorKaramanlioglu, B
dc.contributor.authorMemis, D
dc.contributor.authorKaya, G
dc.contributor.authorPamukçu, Z
dc.date.accessioned2024-06-12T11:19:39Z
dc.date.available2024-06-12T11:19:39Z
dc.date.issued2002
dc.departmentTrakya Üniversitesien_US
dc.description.abstractNeostigmine has been added to local anesthetics for central and peripheral nerve blocks resulting in prolonged, increased anesthesia and improved analgesia. We conducted this study to evaluate the effects of neostigmine when added to prilocaine for IV regional anesthesia (IVRA). Thirty patients undergoing hand surgery were randomly assigned to two groups to receive IVRA. The control group received 1 mL of saline plus 3 mg/kg of prilocaine diluted with saline to a total dose of 40 mL; the study group received 0.5 mg of neostigmine plus 3 mg/kg of prilocaine diluted with saline to a total dose of 40 mL. Sensory and motor block onset and recovery, anesthesia quality determined by an anesthesiologist, anesthesia quality determined by a surgeon, and dryness of the operative field were noted. Heart rate, mean arterial blood pressure, and oxygen saturation values were noted at 1, 5, 10, 20, and 40 min before surgery and after tourniquet release. Time to first analgesic requirement was also noted. Shortened sensory and motor block onset times, prolonged sensory and motor block recovery times, improved quality of anesthesia, and prolonged time to first analgesic requirement were found in the neostigmine group. We conclude that neostigmine as an adjunct to prilocaine improves quality of anesthesia and is beneficial in IVRA.en_US
dc.identifier.doi10.1097/00000539-200211000-00058
dc.identifier.endpage1422en_US
dc.identifier.issn0003-2999
dc.identifier.issue5en_US
dc.identifier.pmid12401636en_US
dc.identifier.scopus2-s2.0-0036828467en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1419en_US
dc.identifier.urihttps://doi.org/10.1097/00000539-200211000-00058
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25287
dc.identifier.volume95en_US
dc.identifier.wosWOS:000178912600058en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofAnesthesia And Analgesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPostoperative Analgesiaen_US
dc.subjectPeripheral Analgesiaen_US
dc.subjectDose-Responseen_US
dc.subjectAcetylcholineen_US
dc.subjectMorphineen_US
dc.subjectNerveen_US
dc.subjectBlocken_US
dc.titleIntravenous regional anesthesia using prilocaine and neostigmineen_US
dc.typeArticleen_US

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