Non-dipper hypertension is associated with slow coronary flow among hypertensives with normal coronary angiogram

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dc.authoridAYDIN, Fatih/0000-0002-1017-1917
dc.authorwosidAkşit, Ercan/L-3292-2019
dc.authorwosidAYDIN, Fatih/ACV-4074-2022
dc.contributor.authorAksit, Ercan
dc.contributor.authorGursul, Erdal
dc.contributor.authorAydin, Fatih
dc.contributor.authorSamsa, Murat
dc.contributor.authorOzcelik, Fatih
dc.date.accessioned2024-06-12T11:03:35Z
dc.date.available2024-06-12T11:03:35Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: A person with a drop of more than 10% in nocturnal arterial blood pressure during the circadian rhythm is referred to as a dipper and one with a smaller decrease is referred to as a non-dipper. In our study, we aimed to compare the thrombolysis in myocardial infarction (TIMI) frame count in non-dipper and dipper hypertensive patient groups who had normal coronary artery angiography. Methods: Patients with normal coronary arteries and with ambulatory blood pressure monitoring follow ups were retrospectively investigated and 60 patients (35%, female) were included in our study. The patients were grouped as dipper (n = 30) and non-dipper (n = 30) hypertensives. Results: The TIMI frame counts in all three coronary arteries and the mean TIMI frame count in the dipper hypertensive patient group were significantly lower than those of the non-dipper hypertensives (right coronary artery TIMI frame count: 16.83 +/- 3.70; 21.63 +/- 3.44, p < 0.001; circumflex artery TIMI frame count: 21.28 +/- 3.52; 25.65 +/- 3.61, p < 0.001; left anterior descending artery TIMI frame count: 34.20 +/- 2.80; 37.05 +/- 3.30, p = 0.001; corrected left anterior descending artery TIMI frame count: 20.05 +/- 1.63; 21.74 +/- 1.95, p = 0.001; mean TIMI frame count: 19.31 +/- 2.3; 22.94 +/- 2.61, p < 0.001). The body mass index (BMI) was 23.79 +/- 2.81 kg/m(2) in the dipper patient group, while it was 25.47 +/- 2.92 in the non-dippers. BMI was found to be significantly higher in the non-dipper group than in the dipper group (p = 0.027). Conclusion: In this study, TIMI frame count, which is a simple, productive, objective and reproducible method for determination of microvascular changes, was found to be higher in non-dipper hypertensive patients than in the dipper patients.en_US
dc.identifier.doi10.5830/CVJA-2016-045
dc.identifier.endpage18en_US
dc.identifier.issn1995-1892
dc.identifier.issn1680-0745
dc.identifier.issue1en_US
dc.identifier.pmid27177043en_US
dc.identifier.scopus2-s2.0-85015350589en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage14en_US
dc.identifier.urihttps://doi.org/10.5830/CVJA-2016-045
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21704
dc.identifier.volume28en_US
dc.identifier.wosWOS:000397242600005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherClinics Cardive Publ Pty Ltden_US
dc.relation.ispartofCardiovascular Journal Of Africaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHypertensionen_US
dc.subjectCoronary Angiographyen_US
dc.subjectTIMI Frame Counten_US
dc.subjectDipperen_US
dc.subjectNon-Dipperen_US
dc.subjectTimi Frame Counten_US
dc.subjectDependent Vascular Relaxationen_US
dc.subjectBlood-Pressure Variationsen_US
dc.subjectAll-Cause Mortalityen_US
dc.subjectCircadian Variationen_US
dc.subjectNitric-Oxideen_US
dc.subjectArtery Flowen_US
dc.subjectUric-Aciden_US
dc.subjectThrombolysisen_US
dc.subjectDiseaseen_US
dc.titleNon-dipper hypertension is associated with slow coronary flow among hypertensives with normal coronary angiogramen_US
dc.typeArticleen_US

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