Technetium-99m sestamibi limb scintigraphy in post-traumatic reflex sympathetic dystrophy: preliminary results

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dc.authoridSarikaya, Ismet/0000-0002-1087-580X
dc.authorwosidSarikaya, Ismet/G-7881-2015
dc.contributor.authorSarikaya, A
dc.contributor.authorSarikaya, I
dc.contributor.authorPekindil, G
dc.contributor.authorFirat, MF
dc.contributor.authorPekindil, YJ
dc.date.accessioned2024-06-12T11:13:27Z
dc.date.available2024-06-12T11:13:27Z
dc.date.issued2001
dc.departmentTrakya Üniversitesien_US
dc.description.abstractReflex sympathetic dystrophy (RSD) has widely variable clinical manifestations. Its pathogenesis remains partially unexplained. RSD is commonly divided into three stages; these stages are not always clearly separable. but staging remains important for correct treatment. Since the disease involves soft tissue alterations as well as bone changes, we decided to investigate whether technetium-99m sestamibi limb imaging can be used to evaluate the soft tissue appearance. Fifteen patients (seven females and eight males; age range 12-68 years) with clinically significant post-fracture RSD were evaluated with both three-phase bone scan (TPBS) and Tc-99m-sestamibi limb scintigraphy. Although, in general, patients with similar duration of disease, clinical stage and TPBS activity tended to have similar patterns of sestamibi uptake, discordant uptake patterns were observed in some patients with clinical stage 1. Thus, of 12 patients with stage I disease, eight had increased Tc-99m-sestamibi activity in the distal part of the affected limb, while three had normal activity and one had decreased activity. All three patients with stage II disease showed normal Tc-99m-sestamibi uptake. Although most of the patients with increased Tc-99m-sestamibi uptake had increased activity on all three phases of the bone scan, there were discordant results between the scan patterns in other patients. On the basis of these findings, we suggest that Tc-99m-sestamibi imaging may contribute to the differentiation between clinical stages and may permit evaluation of the disease course and selection of appropriate therapy. Tc-99m-sestamibi imaging is not, however, a primary diagnostic procedure for RSD.en_US
dc.identifier.doi10.1007/s002590100615
dc.identifier.endpage1522en_US
dc.identifier.issn0340-6997
dc.identifier.issue10en_US
dc.identifier.pmid11685495en_US
dc.identifier.scopus2-s2.0-0034784566en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1517en_US
dc.identifier.urihttps://doi.org/10.1007/s002590100615
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23563
dc.identifier.volume28en_US
dc.identifier.wosWOS:000171621100011en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal Of Nuclear Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectReflex Sympathetic Dystrophyen_US
dc.subjectScintigraphyen_US
dc.subjectTc-99m-Sestamibien_US
dc.subject3-Phase Bone-Scintigraphyen_US
dc.subjectViabilityen_US
dc.subjectExtremityen_US
dc.subjectHanden_US
dc.titleTechnetium-99m sestamibi limb scintigraphy in post-traumatic reflex sympathetic dystrophy: preliminary resultsen_US
dc.typeArticleen_US

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