Extracellular GroEL Promotes adherence of ?rhlA mutant to inert surfaces in Pseudomonas aeruginosa

Basit Öğe Kaydı
dc.authorscopusid8511259600
dc.contributor.authorBukavaz S.
dc.date.accessioned2024-06-12T10:25:47Z
dc.date.available2024-06-12T10:25:47Z
dc.date.issued2019
dc.description.abstractPseudomonas aeruginosa is particularly notorious producing robust biofilm. Bacterial biofilms are three-dimensional systems, attached to inert or living surfaces that are surrounded by an extracellular matrix consisting of; extracellular DNA, proteins, exopolysaccharides, and secondary metabolites (Guilbaud et al., 2017). There are evidences indicating that a biofilm matrix forms micro-environments in which cells are optimally organized to resist stress and use available nutrients. For example, eDNA acts as a biofilm scaffold by binding with other biomolecules, such as peptides, enzymes, proteins, and polysaccharides (Withchurch et al., 2002; Das et al., 2016). Zhang et al., (2015) pointed out that the polysaccharides provide mechanical stability, mediate bacterial adhesion to surfaces, and form a cohesive, three-dimensional network that connects and immobilizes biofilm cells. However, the complex network leading to complete biofilm formation is not well understood. Alayande et al., (2018) reported that the quorum sensing system molecules and unknown secreted proteins involve P. aeruginosa biofilms. © 2019, Egyptian Association for Medical Mycologists (EAMM). All rights reserved..en_US
dc.description.sponsorshipUniversity of Nottingham: -0202278; University of Nottinghamen_US
dc.description.sponsorshipI would like to thank Dr. Frank Rosenau as a mentor of this study, and Institute of Molecular Enzyme Technology in Research Center of Juelich, School of Life Science Center, Biomolecular Sciences, University of Nottingham, Turkey, for the strain and plasmids. This work is one part of the Ph.D Thesis, supported by “Marie-Curie early-stage research Antibiotarget Project”-0202278.en_US
dc.identifier.doi10.21608/NRMJ.2019.28104
dc.identifier.endpage189en_US
dc.identifier.issn2537-0286
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85147913982en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage185en_US
dc.identifier.urihttps://doi.org/10.21608/NRMJ.2019.28104
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16522
dc.identifier.volume3en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEgyptian Association for Medical Mycologists (EAMM)en_US
dc.relation.ispartofNovel Research in Microbiology Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[Abstarct Not Available]en_US
dc.titleExtracellular GroEL Promotes adherence of ?rhlA mutant to inert surfaces in Pseudomonas aeruginosaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu