Evaluation of the effect of intravitreal injections on corneal epithelial, scleral and limbal region changes in diabetic retinopathy by AS-OCT

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dc.authoridCinar, Abdulkadir Can/0000-0003-3709-1922
dc.authoridGUCLU, HANDE/0000-0002-3021-0493
dc.authoridKupeli Cinar, Ayca/0000-0003-4495-9603
dc.contributor.authorCinar, Abdulkadir Can
dc.contributor.authorCinar, Ayca Kupeli
dc.contributor.authorGuclu, Hande
dc.date.accessioned2024-06-12T10:51:53Z
dc.date.available2024-06-12T10:51:53Z
dc.date.issued2024
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurposeT he aim of the study is to evaluate the effects of diabetic retinopathy and intravitreal injections on the corneal, limbal and scleral areas. Methods Patients with diabetes mellitus at different diagnosis and treatment levels were compared among themselves and with the control group in terms of corneal, limbal and scleral aspects with the help of anterior segment optical coherence tomography. In addition, clinical tests such as tear break-up time, Schirmer test-I and ocular surface disease index questionnaire were applied to the patients and the difference between the groups was investigated. Results When the groups were examined in terms of BUT, SCH-I and OSDI, there was a statistically significant difference between control group and diabetic group(p < 0.05). In the limbal region, all measurements are higher than in patients with diabetic eye involvement. Thinning was detected in the scleral area with intravitreal injection (p < 0.05). Conclusion It should be known that DM may cause undesirable changes in the limbal region, and the importance of non-invasive detection with AS-OCT should not be forgotten. Since intravitreal injections for DME cause thinning of the sclera, it can cause various complications, and it may be recommended to change the quadrant in repetitive injection applications.en_US
dc.identifier.doi10.1007/s10792-024-02947-8
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue1en_US
dc.identifier.pmid38329554en_US
dc.identifier.scopus2-s2.0-85184681971en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-024-02947-8
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18507
dc.identifier.volume44en_US
dc.identifier.wosWOS:001167650900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnterior Segment Optical Coherence Tomographyen_US
dc.subjectCorneaen_US
dc.subjectDiabetic Retinopathyen_US
dc.subjectIntravitreal Injectionen_US
dc.subjectScleraen_US
dc.subjectMacular Edemaen_US
dc.subjectThicknessen_US
dc.titleEvaluation of the effect of intravitreal injections on corneal epithelial, scleral and limbal region changes in diabetic retinopathy by AS-OCTen_US
dc.typeArticleen_US

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