Synthesis of platinum(II) complexes of 1-aryl-3-(benzimidazole-2-yl)- pyrazole-4-ketoximes and studies on their cytotoxic effects
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this research, synthesis of some complexes in the presence ofPt(II) were studied. The structure of the compounds were elucidated by IR, 1H-NMR, Mass and Elemental Analyses. The cytotoxicity of Pt-complex was evaluated. The cellular responses through MTT method were measured in normal rat embryo fibroblast line F2408 andH-ras active-rat embryo fibroblast line 5RP7.
Açıklama
Anahtar Kelimeler
Ketoximes; Metal Complexes; Mtt, Antineoplastic Agent; Oxime Derivative; Platinum Complex; Animal Cell; Antineoplastic Activity; Article; Cell Viability; Controlled Study; Cytotoxicity; Drug Structure; Drug Synthesis; Embryo; Nonhuman; Physical Chemistry; Proton Nuclear Magnetic Resonance; Rat
Kaynak
Turkish Journal of Pharmaceutical Sciences
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
5
Sayı
1
