Pilomatrix Carcinoma with Pulmonary Metastasis
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkiye Klinikleri
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A rare malignancy, pilomatrix carcinoma (PC) histologically originates from matrix cells in skin hair follicles. Pathologically, it can be confused with squamous cell carcinoma (SCC). A 56-year-old male was referred to us with a diagnosis of SCC of the right lung. After initial histopathological evaluation, the lung tissue was re-examined immunohistochemically, and a diagnosis of metastatic PC was made. Due to an absence of standardized treatment for metastatic PC, we administered a combination of carboplatin and paclitaxel due to its wide-spectrum anti-tumoral activities; however, the disease progressed despite first-line treatment. Although cyclophosphamide and etoposide were administered orally as a second-line therapy, the patient showed little progress and passed away despite two chemotherapy courses. Hence, the diagnosis, treatment, and prognosis of this rare tumor present several challenges. We aimed to contribute to this existing dilemma with our case report and literature review. © 2024 by Turkish Society of Medical Oncology.
Açıklama
Anahtar Kelimeler
Pilomatrixoma; Pulmonary Metastasis; Skin Neoplasms, Carboplatin; Cyclophosphamide; Etoposide; Paclitaxel; Abdominal Tumor; Adult; Antineoplastic Activity; Article; Biopsy; Cancer Combination Chemotherapy; Cancer Growth; Cancer Prognosis; Case Report; Clinical Article; Computer Assisted Tomography; Death; Excision; Follow Up; Histopathology; Human; Human Tissue; Immunohistochemistry; Intensive Care Unit; Lung Metastasis; Lung Parenchyma; Male; Middle Aged; Multiple Cycle Treatment; Pilomatrix Carcinoma; Squamous Cell Lung Carcinoma; Thorax Radiography
Kaynak
Journal of Oncological Science
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
10
Sayı
1
