Corneal endothelial polymegethism and pleomorphism induced by daily-wear rigid gas-permeable contact lenses

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Tarih

2002

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Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Purpose. To determine if there are any corneal endothelial cell size and shape changes (and the time course of these changes) in subjects wearing rigid high gas-permeable (RGP) contact lenses for daily wear. Methods. Ninety-seven eyes of 57 new wearers were fitted with a fluoroperm contact lens material (Persecon92E, oxygen transmissibility (Dk)= 92×10-11). Prior to lens wear and after 1 week, 1 month, 3 months, 6 months, and 1 year, noncontact endothelial photographs were taken. Maximum cell size/Minimum cell size (Max/Min) was measured as an index of polymegethism and the relative frequency of 5-, 6-, and 7-sided cells was evaluated. Results. An increase in the ratio of Max/Min was present 1 week after lens fitting and increased further over the subsequent year. This study showed significant increase in endothelial polymegethism and in the relative frequency of 7-sided cells, but a significant decrease in the relative frequency of 6-sided cells. Conclusions. Daily-wear high Dk gas-permeable contact lenses can cause endothelial polymegethism and pleomorphism similar to those caused by soft and hard contact lenses.

Açıklama

Anahtar Kelimeler

Corneal Endothelium; Pleomorphism; Polymegethism; Rigid Gas-Permeable Contact Lenses; Specular Microscopy, Adult; Article; Cell Size; Cell Structure; Contact Lens; Controlled Study; Cornea Disease; Cornea Endothelium; Female; Gas Permeability; Hard Contact Lens; Histopathology; Human; Major Clinical Study; Male; Pathophysiology; Soft Contact Lens; Specular Microscopy; Adolescent; Adult; Cell Count; Cell Size; Child; Contact Lenses; Corneal Diseases; Endothelium, Corneal; Female; Humans; Male; Middle Aged

Kaynak

CLAO Journal

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

28

Sayı

1

Künye