R-R interval variability analysis with electromyography detects early autonomic neuropathy in diabetic children
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: Autonomic neuropathy may exist together with peripheral neuropathy, especially in diabetic patients and it is important to diagnose early autonomic neuropathy especially cardiac one because of their serious effects on mortality and morbidity rates. A decrement of R-R interval variability (RRIV) is a good marker for cardiac autonomic neuropathy. We analyzed RRIV with an alternative method using electromyography machine, and assessed the RRIV in diabetic children who have no clinical sign of cardiac autonomic neuropathy. Method: 64 healthy (mean age 9.5±1.8) and 33 type 1 diabetic (mean age 10.2±2.8) children who have no peripheral neuropathy were included. Recording was made on EMG machine and RRIV was obtained during quiet and deep breathing. Two surface electrodes were placed on the chest, and using triggering mode and delay line, two QRS complexes displayed on the screen. Since the first QRS complex was triggering potential, variation in timing of the second QRS complex represented variation in the R-R interval. RRIV was expressed as a percentage of the average R-R interval. Results: In healthy children, RRIV was 23.9±9.5% in rest and 25.6±10.2% in hyperventilation. In diabetic children, RRIV was 17,4±6.6% in rest, 22±8.9% in hyperventilation. Resting RRIV was lower in diabetic children than healthy children (p=0.001), but there was no difference between groups in hyperventilation (p=0.4). Discussion: Our findings suggest that RRIV may have value to determine cardiac autonomic neuropathy in diabetic children who have no clinical sign of cardiac autonomic neuropathy. Conclusion: The technique, we used is a non time consuming procedure, easily performed in EMG laboratory, and is a simple way of reflecting autonomic dysfunction of the heart.
Açıklama
Anahtar Kelimeler
Autonomic Neuropathy; Diabetes Mellitus; Electromyography; R-R Interval Variability, Adolescent; Article; Autonomic Neuropathy; Breathing; Cardica Autonomic Neuropathy; Child; Comparative Study; Controlled Study; Diabetes Mellitus; Diabetic Patient; Electrode; Electromyography; Female; Human; Hyperventilation; Major Clinical Study; Male; Qrs Complex; Rr Interval
Kaynak
Yeni Symposium
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
46
Sayı
3
