Suzuki coupling reactions catalyzed by Schiff base supported palladium complexes bearing the vitamin B6 cofactor
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Novel Schiff bases were synthesized by condensing aromatic amines with pyridoxal-5'-phosphate and charac-terized by using FT-IR, H-1 NMR, and C-13 NMR spectroscopic techniques. The resulting Schiff bases were utilized as bidentate ligands, coordinating via imine nitrogen and phenolate oxygen atoms, to stabilize palladium ions. Aryl substituents on imine nitrogen allowed for fine tuning of the stereoelectronic properties of the Schiff bases. The catalytic activity of the selected palladium complexes was investigated in the Suzuki cross-coupling reaction of a series of aryl halides with boronic acids in H2O/EtOH (1:1). Out of four complexes investigated in the cross-coupling reactions, Pd(L-8)(2), bearing a methoxy substituent on aryl imine, showed the highest activity at low catalyst loading. The scope of the reaction was also investigated with 26 samples.
Açıklama
Anahtar Kelimeler
Schiff Base, Pyridoxal-5-Phosphate, Homogeneous Palladium Catalyst, Carbon-Carbon Cross Coupling
Kaynak
Molecular Catalysis
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
505
