The prognostic value of atrial and brain natriuretic peptides, troponin I and C-reactive protein in patients with sepsis

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dc.authorscopusid8864145800
dc.authorscopusid7003369853
dc.authorscopusid7003311524
dc.authorscopusid6603267445
dc.authorscopusid57197111786
dc.contributor.authorYucel T.
dc.contributor.authorMemiş D.
dc.contributor.authorKaramanlioglu B.
dc.contributor.authorSüt N.
dc.contributor.authorYuksel M.
dc.date.accessioned2024-06-12T10:28:32Z
dc.date.available2024-06-12T10:28:32Z
dc.date.issued2008
dc.description.abstractAim: To investigate the plasma levels of atrial and brain natriuretic peptides (ANP and BNP), cardiac troponin I (cTnI) and C-reactive protein (CRP) as prognostic factors for survival in patients with sepsis. Method: Evaluation of serum levels of ANP, BNP, cTnI and CRP of patients an admission to an intensive care unit, two days later, and on the day of discharge from the intensive care unit or on the day of death. Results: ANP levels were significantly higher in the nonsurviving patients (day 1: 70.00±49.54 pg/mL; day 2: 138.85±143.15 pg/mL; and died/discharged day: 375.70±262.66 pg/mL) than surviving patients (day 1: 23.96±29.93 pg/mL; day 2: 10.06±6.03 pg/ML; died/discharged. day: 6.68±100.98 pg/mL, P<0.001). The BNP levels were significantly higher in the nonsurvivors (day 1: 254.78±308.62 pg/mL; day 2: 383.22±307.19 pg/mL; and died/discharged day: 696.47±340.33 pg/mL), than survivors (day 1: 13.72±12.95 pg/mL; day 2: 7.20±5.85 pg/mL; died/discharged day: 4.51±4.64 pg/mL, P<0.001). The cTnI levels were significantly higher in the nonsurviving patients (day 2: 0.16±0.38 ?g/L; died/discharged day: 0.78±2.48 ?g/L) than surviving patients (day 2: 0.04±0.07 ?g/L; died/discharged day: 0.02±0.01 ?g/L, P<0.05). The CRP levels were significantly higher in the nonsurvivors (day 2: 119.3±71.5 mg/L; and died/discharged day: 145.7±74.7 mg/L) than sumavors (day 2: 57.0±29.7 mg/L; died/discharged day: 26.8±24.0 mg/L, P<0,05). There were no significont differences between nonsurvivors and survivors for cTnI and CRP on day 1. Conclusion: With the exception of cTnI and CRP on day 1, all of the parameters were significantly powerful to determine nonsurvivors on all days. Among these variables, BNP was the most powerful diagnostic parameter for the prediction of nonsurvivors on all days. © 2008 Pulsus Group Inc. All rights reserved.en_US
dc.identifier.endpage188en_US
dc.identifier.issn1205-6626
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-63449126664en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage183en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17274
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofExperimental and Clinical Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectC-Reactive Protein; Intensive Care Unit; Natriuretic Peptides; Prognosis; Sepsis; Troponin Ien_US
dc.subjectAtrial Natriuretic Factor; Brain Natriuretic Peptide; C Reactive Protein; Troponin I; Adult; Aged; Apache; Article; Clinical Article; Controlled Study; Critically Ill Patient; High Risk Patient; Human; Intensive Care Unit; Mortality; Prediction; Prognosis; Protein Analysis; Protein Blood Level; Sepsis; Survivalen_US
dc.titleThe prognostic value of atrial and brain natriuretic peptides, troponin I and C-reactive protein in patients with sepsisen_US
dc.typeArticleen_US

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