An adult patient with common B-cell acute lymphoblastic leukaemia who presented with pancreatic involvement, description of the second adult case and review of paediatric cases
Küçük Resim Yok
Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
BMJ Publishing Group
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Pancreatic involvement in acute lymphoblastic leukaemia (ALL) may go unrecognised. There are only a few paediatric cases; nevertheless, presentation with pancreatic involvement in an adult patient with ALL has been reported rarely. Our 52-year-old male patient came to us with abdominal pain, nausea and vomiting; he had pancreatic enlargement on CT. He was diagnosed with common B-cell ALL with pancreatic involvement. The patient obtained haematological remission and the pancreatic enlargement regressed after chemotherapy, but later he had central nervous system and liver relapses. He died 6 months after diagnosis because of progressive pneumonia and chemotherapy-resistant ALL with multiple extramedullary relapses. Copyright 2014 BMJ Publishing Group. All rights reserved.
Açıklama
Anahtar Kelimeler
Cd19 Antigen; Cd22 Antigen; Cd45 Antigen; Cd79a Antigen; Common Acute Lymphoblastic Leukemia Antigen; Cytarabine; Daunorubicin; Etoposide; Hla Dr Antigen; Mercaptopurine; Methotrexate; Prednisolone; Vincristine; Abdominal Pain; Abdominal Radiography; Abdominal Tenderness; Acute Lymphoblastic Leukemia; Acute Pancreatitis; Adult; Article; Bone Marrow Biopsy; Cancer Mortality; Cancer Recurrence; Case Report; Central Nervous System Metastasis; Computer Assisted Tomography; Cranial Nerve Paralysis; Flow Cytometry; Follow Up; Human; Human Tissue; Laboratory Diagnosis; Leukemia Remission; Liver Metastasis; Male; Middle Aged; Nausea; Pancreas Metastasis; Physical Examination; Pneumonia; Priority Journal; Splenomegaly; Treatment Outcome; Vomiting
Kaynak
BMJ Case Reports
WoS Q Değeri
Scopus Q Değeri
Q3