Early Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusion

dc.contributor.authorGuler, Sibel
dc.contributor.authorUtku, Ufuk
dc.contributor.authorAynaci, Ozer
dc.date.accessioned2024-06-12T11:15:55Z
dc.date.available2024-06-12T11:15:55Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to assess infarct localization, clinical signs, and prognostic factors in cases with unilateral symptomatic total internal carotid occlusion. Methods: In total, 101 patients who had a diagnosis of symptomatic unilateral carotid occlusion in the Department of Neurology, Trakya University Faculty of Medicine, between January 2008 and May 2012, were included in this study. The relationship between infarct localizations and prognosis of patients was evaluated by cranial magnetic resonance imaging (MRI) and diffusion-weighted MRI. The condition of ipsilateral middle cerebral artery (MCA) and posterior communicating arteries (PCoAs) was assessed by cranial and cervical magnetic resonance angiography besides opposite carotid. Patients were evaluated by modified Rankin Scale in terms of prognosis at discharge and after 3 months. Furthermore, they were evaluated in terms of risk factors, such as cigarette and alcohol use, presence of temporary ischemic attack and stroke history, hypertension, diabetes mellitus, coronary artery disease, previous myocardial infarction, hyperlipidemia, and peripheral vascular disease. Results: Territorial infarct was commonly seen as acute ischemic stroke pattern especially in cases with a poor MCA circulation and insufficient collateral circulation. Development of territorial stroke, occlusion of MCA, and nonvisualization of PCoA were found to be associated with poor prognosis. Conclusions: In unilateral symptomatic intracranial carotid artery occlusion, poor prognosis and high mortality-associated territorial stroke pattern is frequently observed. Besides, presence of severe stenosis or occlusion and absence of collateral circulation in MCA are associated with poor prognosis.en_US
dc.identifier.doi10.1016/j.jstrokecerebrovasdis.2014.02.009
dc.identifier.endpage1914en_US
dc.identifier.issn1052-3057
dc.identifier.issn1532-8511
dc.identifier.issue7en_US
dc.identifier.pmid24746551en_US
dc.identifier.scopus2-s2.0-84905450129en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1908en_US
dc.identifier.urihttps://doi.org/10.1016/j.jstrokecerebrovasdis.2014.02.009
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24122
dc.identifier.volume23en_US
dc.identifier.wosWOS:000341484400023en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal Of Stroke & Cerebrovascular Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSymptomatic Unilateral Carotid Occlusionen_US
dc.subjectInfarct Patternen_US
dc.subjectWillis Polygonen_US
dc.subjectTreatmenten_US
dc.subjectPrognosisen_US
dc.subjectCerebral Infarctsen_US
dc.subjectDiseaseen_US
dc.subjectStrokeen_US
dc.subjectPatternsen_US
dc.subjectFlowen_US
dc.subjectCircleen_US
dc.subjectWillisen_US
dc.subjectBrainen_US
dc.subjectAngiographyen_US
dc.subjectCten_US
dc.titleEarly Clinical Signs, Lesion Localization, and Prognostic Factors in Unilateral Symptomatic Internal Carotid Artery Occlusionen_US
dc.typeArticleen_US

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