The variation in chronic widespread pain and other symptoms in fibromyalgia patients. The effects of menses and menopause

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dc.authorscopusid7003635356
dc.authorscopusid6603837809
dc.contributor.authorPamuk Ö.N.
dc.contributor.authorÇakir N.
dc.date.accessioned2024-06-12T10:29:20Z
dc.date.available2024-06-12T10:29:20Z
dc.date.issued2005
dc.description.abstractObjectives: We determined the relationship between the menstrual cycle and fibromyalgia (FM) symptoms in premenopausal women. In addition, we compared the clinical features of FM patients diagnosed pre-and postmenopausally. Methods: We included 80 premenopausal, and 72 postmenopausal patients with FM. All patients were questioned about the severity of their pain and symptoms of FM by using a visual analog scale (VAS). In addition, the patients were asked questions about symptoms of somatization, depression and anxiety. Postmenopausal subjects were asked about the change in their FM symptoms with the onset of menopause; and premenopausal subjects were asked whether their FM symptoms changed during the menses. In addition, 40 premenopausal patients were requested to fill in a diary about their FM symptoms using VAS throughout one menstrual cycle. Results: Postmenopausal patients had more severe pain on VAS (p = 0.048). Of all the postmenopausal females, 25% said that their FM symptoms started with the onset of menopause and 26.4% said that the severity of their previous symptoms increased after menopause. Of all the premenopausal females, 45% admitted to higher pain severity and 57.5% to a higher fatigue severity during the menses. The patients who defined an increase in their symptoms during the menses were the ones with higher sleep disturbance scores, more somatization symptoms and more tender points (p values < 0.05). The results of the diaries revealed that the mean pain and fatigue scores in the menstrual and luteal phases were higher than the scores in the follicular and premenstrual phases (p values < 0.05). Conclusions: The menstrual cycle and the onset of menopause affect pain and the severity of other FM-related symptoms in approximately one half of the subjects. © Copyright Clinical and Experimental Rheumatology 2005.en_US
dc.identifier.endpage782en_US
dc.identifier.issn0392-856X
dc.identifier.issue6en_US
dc.identifier.pmid16396694en_US
dc.identifier.scopus2-s2.0-29944434789en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage778en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17710
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofClinical and Experimental Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic Widespread Pain; Fibromyalgia; Menopause; Menses; Menstrual Cycleen_US
dc.subjectAdolescent; Adult; Aged; Anxiety Disorder; Article; Chronic Pain; Clinical Examination; Clinical Feature; Correlation Analysis; Depression; Disease Exacerbation; Disease Severity; Female; Fibromyalgia; Follicular Phase; Human; Interview; Luteal Phase; Major Clinical Study; Medical Documentation; Menstrual Cycle; Muscle Fatigue; Postmenopause; Premenopause; Priority Journal; Scoring System; Sleep Disorder; Somatization; Symptomatology; Visual Analog Scale; Adolescent; Adult; Aged; Chronic Disease; Female; Fibromyalgia; Humans; Menopause; Menstruation; Middle Aged; Pain; Postmenopause; Severity Of Illness Indexen_US
dc.titleThe variation in chronic widespread pain and other symptoms in fibromyalgia patients. The effects of menses and menopauseen_US
dc.typeArticleen_US

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