Early oxidative status in adult patients with isolated traumatic brain injury

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dc.authoridKocyigit, Abdurrahim/0000-0003-2335-412X
dc.authoridKaya, Halil/0000-0003-2005-6100;
dc.authorwosidKocyigit, Abdurrahim/P-8685-2019
dc.authorwosidKaya, Halil/ABH-5489-2020
dc.authorwosidGokdemir, Mehmet Tahir/JRX-0261-2023
dc.contributor.authorSogut, Ozgur
dc.contributor.authorKaya, Halil
dc.contributor.authorGokdemir, Mehmet Tahir
dc.contributor.authorSolduk, Leyla
dc.contributor.authorDokuzoglu, Mehmet Akif
dc.contributor.authorSayhan, Mustafa Burak
dc.contributor.authorKaya, Atilhan
dc.date.accessioned2024-06-12T11:02:56Z
dc.date.available2024-06-12T11:02:56Z
dc.date.issued2012
dc.departmentTrakya Üniversitesien_US
dc.description6th European Congress on Emergency Medicine / 12th Annual Meeting of SweSEM -- OCT 11-14, 2010 -- Stockholm, SWEDENen_US
dc.description.abstractAim: To investigate oxidative and antioxidative status, as well as the Glasgow Coma Scale (GCS) and Revised Trauma Score (RTS), reflecting injury severity and neurological outcome during the early posttraumatic period in patients with isolated traumatic brain injury (TBI). Materials and methods: Fifty-one adult patients with TB! and 45 eligible healthy volunteers as control subjects were enrolled. Plasma total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) were calculated as biomarkers of early oxidative changes in serum using a novel automated method. Results: TOS levels and OSI values were significantly higher in nonsurvivors compared with those in survivors. However, there was no significant difference in TAS levels between survivors and nonsurvivors. GCS and RTS showed negative correlations with TOS levels, but neither was significantly related to OSI levels. Furthermore, GCS scores were negatively correlated with TAS levels, whereas RTS scores were not significantly related to TAS levels. Conclusion: Patients with isolated TBI are exposed to potent oxidative stress. TOS, as an early oxidative stress biomarker, might reflect the severity of cerebral insult in those patients.en_US
dc.identifier.doi10.3906/sag-1109-35
dc.identifier.endpage1019en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-84868683598en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1010en_US
dc.identifier.trdizinid142754en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1109-35
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/142754
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21475
dc.identifier.volume42en_US
dc.identifier.wosWOS:000309796300010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHead Injuryen_US
dc.subjectClinical Outcomeen_US
dc.subjectOxidative Stress Indexen_US
dc.subjectTotal Oxidant Statusen_US
dc.subjectTotal Antioxidant Statusen_US
dc.subjectTotal Oxidant Statusen_US
dc.subjectCritically-Ill Patientsen_US
dc.subjectHead-Injuryen_US
dc.subjectFree-Radicalsen_US
dc.subjectStressen_US
dc.subjectRatsen_US
dc.subjectClassificationen_US
dc.subjectMortalityen_US
dc.subjectSeverityen_US
dc.titleEarly oxidative status in adult patients with isolated traumatic brain injuryen_US
dc.typeConference Objecten_US

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