Qualitative and quantitative evaluation of the marketing Passiflora incarnata L. formulations in Turkey
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Marmara University
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Passiflora incarnata L. (Passifloraceae) has been traditionally used to treat ailments such as dysmenorrhoea, insomnia, epilepsy and neuralgia. In this study, qualitative and quantitative analyses of P. incarnata products in the Turkish market were studied via High-Performance Thin-Layer Chromatography (HPTLC) and High-Performance Liquid Chromatography (HPLC) and vitexin, isovitexin, orientin and isoorientin were used as bioactive marker compounds. Seven herbal tea samples (T1-7) composing P. incarnata herb, eighteen capsules/tablets/powders (C1-18) and four syrups (S1-4) containing P. incarnata extract were purchased from pharmacies, markets, herbalists or e-commerce websites in Turkey. Comparing HPTLC fingerprinting profiles of the reference plant (P. incarnata) with the samples indicated that only T1, C1-C3, C5, C7, C11, C12, C14, C15 and S1 showed similar chemical fingerprints with the reference plant material. On the HPLC analysis, the total ratio of investigated compounds was 6.33% and 2.08% in hydroalcoholic (70% EtOH) and aqueous extracts of reference P. incarnata, respectively. Furthermore, hydroalcoholic extract of T1 was found to possess higher content (6.40%) than other tested tea samples (T2-6). However, based on the morphological characteristics, the tea sample (T7) was identified as Jerusalem thorn (Paliurus spina-christi) fruits. Among the food supplements (C1-18), only nine were determined to contain the reference molecules (3.301-0.827%), consistent with HPTLC results, and C1 exerted the highest total percentage. To conclude, most of the marketing P. incarnata products in Turkey were adulterated or contained lower amounts of bioactive components. © 2023 Marmara University Press.
Açıklama
Anahtar Kelimeler
High-Performance Liquid Chromatography; High-Performance Thin-Layer Chromatography; Passiflora Incarnata; Passifloraceae; Quality Control, Isoorientin; Isovitexin; Orientin; Passiflora Incarnata Extract; Vitexin; Aqueous Solution; Article; Chemical Fingerprinting; Derivatization; Dietary Supplement; Drug Capsule; Drug Formulation; Drug Marketing; Drug Quality; Herbal Tea; High Performance Liquid Chromatography; High Performance Thin Layer Chromatography; Limit Of Detection; Limit Of Quantitation; Measurement Accuracy; Measurement Precision; Morphological Trait; Pharmacy (Shop); Powder; Qualitative Analysis; Quality Control; Quantitative Analysis; Syrup; Tablet; Turkey (Republic)
Kaynak
Journal of Research in Pharmacy
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
27
Sayı
2
