An increased frequency of gallbladder stones in rheumatoid arthritis patients.: Factors related to gallbladder stone formation

Basit Öğe Kaydı
dc.authoridUmit, Hasan/0000-0002-3651-4180
dc.authorwosidUmit, Hasan/T-6236-2019
dc.authorwosidCakir, Necati/AAG-7283-2019
dc.contributor.authorPamuk, O. N.
dc.contributor.authorUmit, H.
dc.contributor.authorUnlu, E.
dc.contributor.authorKoker, I. H.
dc.contributor.authorCakir, N.
dc.date.accessioned2024-06-12T11:13:40Z
dc.date.available2024-06-12T11:13:40Z
dc.date.issued2006
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective. In this study, we determined the frequency of gallbladder stone (GBS) in rheumatoid arthritis (RA) patients and evaluated factors which could affect the formation of GBS such as lipids and the GB motilities of the patients. Methods. One hundred and thirteen RA patients (92F, 21M, mean disease duration: 8.9 years) and 117 healthy controls (94F, 23M) were included. In all RA patients, the clinical findings were recorded down; biochemical parameters and body mass index (BMI) were determined; and, abdominal ultrasonography was performed. In addition, 16 RA patients and 20 controls who were age-matched were randomly chosen for GB emptying monitored by ultrasound at 30-minute intervals for 2 hours after a mixed meal. Fasting volume (FV), residual volume (RV) and ejection fraction (EF) for all GBs were assessed. Results. There was a tendency towards a higher frequency of GBS including cholecystectomy (11 GBS, 11 cholecystectomy, 19.5%) in RA patients when compared to controls (8 GBS, 5 cholecystectomy, 11.1%) (p = 0.08). The frequency of GBS plus cholecyctectomy in female RA patients (22.8%) was significantly higher than the control group (11.7%, p = 0.044). Logistic regression analysis showed that only older age was significantly associated with the presence of GBS in RA (OR:1.05, p = 0.048). There was no difference between the 2 groups in FV (p > 0.05). RV PRV and EF were significantly higher in RA patients than in the control group (p < 0.05). Conclusions. We diagnosed a higher frequency of GBS in female RA patients when compared to controls. Impaired GB motility in RA patients might contribute to an increased incidence of GBS development.en_US
dc.identifier.endpage320en_US
dc.identifier.issn0392-856X
dc.identifier.issn1593-098X
dc.identifier.issue3en_US
dc.identifier.pmid16870102en_US
dc.identifier.startpage317en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23639
dc.identifier.volume24en_US
dc.identifier.wosWOS:000239447900017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherClinical & Exper Rheumatologyen_US
dc.relation.ispartofClinical And Experimental Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectGallstoneen_US
dc.subjectGallbladder Motilityen_US
dc.subjectNon-Steroidal Anti-Inflammatory Drugsen_US
dc.subjectCholesterol-Gallstone Formationen_US
dc.subjectReal-Time Ultrasonographyen_US
dc.subjectRisk-Factorsen_US
dc.subjectProstaglandin Synthesisen_US
dc.subjectDiabetes-Mellitusen_US
dc.subjectObese Patientsen_US
dc.subjectWeight-Lossen_US
dc.subjectDiseaseen_US
dc.subjectPrevalenceen_US
dc.subjectAspirinen_US
dc.titleAn increased frequency of gallbladder stones in rheumatoid arthritis patients.: Factors related to gallbladder stone formationen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu