The effect of mental stress on seminal MDA and semen parameters

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dc.authorscopusid8713093200
dc.authorscopusid56006386400
dc.authorscopusid9633125800
dc.authorscopusid9637115900
dc.contributor.authorGözen A.S.
dc.contributor.authorEskiocak S.
dc.contributor.authorKiliç A.S.
dc.contributor.authorMolla S.
dc.date.accessioned2024-06-12T10:28:44Z
dc.date.available2024-06-12T10:28:44Z
dc.date.issued2005
dc.description.abstractIntroduction: The prevalence of unexplained infertility is 15% among all infertility cases and mental distress has been suggested as a cause of it. Emotional stress can cause some abnormalities in semen parameters, although the basic biochemical principles of the relationship between mental stress and semen parameters are poorly understood. Recently there is emerging interest in reactive oxygen species (ROS) with respect of their unfavorable effect on fertility as a result of lipid peroxidation. In this study, the effects of mental stress on the Malondialdehyde (MDA) levels, an indirect indicator of lipid peroxidation and semen parameters were investigated. Materials and methods: Semen samples were collected from 36 healthy volunteer students of the fourth semester of the medical school just before (stress period) and 3 months after (non-stress period) the final examinations by masturbation. Psychological stress of the participants was measured with the State Trait Anxiety Inventory. After standard semen analysis, MDA activity was measured in the seminal plasma. The data of the stress and non-stress periods were compared via paired samples t test. Correlation analysis between MDA levels and sperm parameters was made for both stress and non-stress periods. A value of p less than 0.05 was considered statistically significant. Correlations between MDA levels and sperm parameters also were examined by Pearson Correlation test. A value of p less than 0.05 was considered statistically significant. Results: During the stress period, stress scores were higher compared with the non-stress period (43.61±10.71 vs. 37.67±9.61). Our data showed that, sperm count, percentage of progressive motility and percentage of normal morphology significantly decreased during the stress period. Seminal plasma MDA levels were significantly higher during the stress period compared with the non-stress period (50.19±48.22 vs. 16.19±22.59 nmol/109 spermatazoa). There was a positive correlation between seminal plasma MDA levels and percentage immobility at 1/2 and 2nd hours at the stress period. And seminal plasma MDA level was found to correlate negatively with the percentage normal morphology and total sperm count. Conclusion: Our results indicate that mental stress can cause an unfavorable effect on semen parameters. Increased seminal plasma MDA levels at stress period may be a result of overproduction of ROS in semen. We would suggest that stress may cause oxidative stress in semen and in this way it could be responsible for male subfertility. We think that this subject deserves further studies.en_US
dc.identifier.endpage362en_US
dc.identifier.issn1300-5804
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-28244483837en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage356en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17384
dc.identifier.volume31en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Uroloji Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMental Stress; Semen Parameters; Seminal Plasma Mdaen_US
dc.subjectLipid; Malonaldehyde; Reactive Oxygen Metabolite; Article; Controlled Study; Correlation Analysis; Examination; Human; Human Cell; Human Experiment; Lipid Peroxidation; Male; Male Infertility; Masturbation; Medical Student; Mental Stress; Morphology; Normal Human; Oxidative Stress; Psychoanalysis; Sampling; Scoring System; Semen Analysis; Spermatozoon Count; Spermatozoon Motility; Statistical Significance; Student T Testen_US
dc.titleThe effect of mental stress on seminal MDA and semen parametersen_US
dc.title.alternativeZihinsel Stresin Seminal MDA ve Semen Parametreleri Üzerine Etkisien_US
dc.typeArticleen_US

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