Comparison of intravenous sufentanil and bupivacaine administration for preventing haemodynamic responses to Mayfield Holder in craniotomies

Küçük Resim Yok

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Aim: Our aim was to compere intravenous sufentanil and scalp infiltration with bupivacaine on the haemodynamic response to placement of the Mayfield head Holder used for neurosurgery. Materials and Methods: Fifty-nine ASA I/II patients aged 20-58 years undergoing craniotomy were randomized into 3 groups. Group S (n=20) received intravenous sufentanil (10 ?g) and scalp infilitration with 0.9% NaCl, Group B (n=20) received intravenous 0.9% NaCl + scalp infilitration with % 0.5 bupivacaine (10 mg); Group K (n=19) received intravenous and scalp infilitration with 0.9% NaCl. Systolic, diastolic and mean arterial pressures and heart rate were recorded before and after induction; infiltration and Mayfield frame application. Results: Sufentanil significantly decreased arterial pressures and heart rate in Group S (p<0.01; p<0.001). No significant haemodynamic differences were recorded after infiltration in Groups B and K (p>0.05). Following application of the Mayfield frame arterial pressures and heart rate increased in Group K (p<0.001) and remained high after 5 minutes (p<0.01, p<0.001). In Group B, frame application was associated with increased diastolic (p<0.05) and mean (p<0.01) arterial pressures and heart rate (p<0.05). Diastolic and mean arterial pressures remained elevated after 5 minutes (p<0.05). In Group S, pin insertion did not increase haemodynamic parameters rather the lower haemodynamic values observed following sufentanil administration persisted throughout the study period. Conclusion: Intravenous sufentanil (10 ?g) and local administration of % 0.5 bupivacaine (10 mg) blunted the haemodynamic responses to pin insertion during Mayfield frame application. Following sufentanil administration, blood pressure and heart rate was decreased throughout the period of study.

Açıklama

Anahtar Kelimeler

Bupivacaine; Sufentanil, Atracurium; Bupivacaine; Fentanyl; Sodium Chloride; Sufentanil; Thiopental; Adult; Anesthesia Induction; Article; Clinical Trial; Controlled Clinical Trial; Controlled Study; Craniotomy; Diastolic Blood Pressure; Female; Heart Rate; Hemodynamics; Human; Intravenous Anesthesia; Local Anesthesia; Major Clinical Study; Male; Mean Arterial Pressure; Neurosurgery; Oxygen Saturation; Randomized Controlled Trial; Scalp; Surgical Instrument; Systolic Blood Pressure

Kaynak

Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

33

Sayı

3

Künye