Hyponatremia and takotsubo syndrome: a review of pathogenetic and clinical implications

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dc.authoridPALABIYIK, Orkide/0000-0002-3488-3740
dc.contributor.authorYalta, Kenan
dc.contributor.authorPalabiyik, Orkide
dc.contributor.authorGurdogan, Muhammet
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2024-06-12T11:15:59Z
dc.date.available2024-06-12T11:15:59Z
dc.date.issued2024
dc.departmentTrakya Üniversitesien_US
dc.description.abstractHyponatremia is a common electrolyte abnormality with important prognostic and therapeutic implications. It might exert detrimental effects on various organ systems including the central nervous system (CNS), bone, and heart along with its potential association with poor quality of life. These adverse effects might be largely mediated through a variety of mechanisms including osmotic stress, dysfunctional transmembrane exchangers, and enhanced oxidative stress.Interestingly, hyponatremia might also have an important association with takotsubo syndrome (TTS) that has been universally considered as a reversible form of cardiomyopathy usually emerging in response to various stressors. In this context, severe hyponatremia was previously reported to serve as a direct trigger of TTS evolution largely through its potential impact on CNS and heart. However, pathogenetic and clinical implications of hyponatremia still need to be thoroughly evaluated in patients with TTS. This paper aims to analyze the clinical features of published cases with TTS primarily triggered by hyponatremia and also aims to discuss the association between hyponatremia and TTS from a broader perspective.en_US
dc.identifier.doi10.1007/s10741-023-10344-z
dc.identifier.endpage44en_US
dc.identifier.issn1382-4147
dc.identifier.issn1573-7322
dc.identifier.issue1en_US
dc.identifier.pmid37698728en_US
dc.identifier.scopus2-s2.0-85170850277en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage27en_US
dc.identifier.urihttps://doi.org/10.1007/s10741-023-10344-z
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24154
dc.identifier.volume29en_US
dc.identifier.wosWOS:001064515100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofHeart Failure Reviewsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTakotsubo Syndromeen_US
dc.subjectHyponatremiaen_US
dc.subjectPathogenesisen_US
dc.subjectClinical Implicationsen_US
dc.subjectHyponatremia Correctionen_US
dc.subjectAdrenergic Dischargeen_US
dc.subjectActivated Protein-Kinaseen_US
dc.subjectPreserved Ejection Fractionen_US
dc.subjectCongestive-Heart-Failureen_US
dc.subjectAmino-Acid Catabolismen_US
dc.subjectCardiac-Hypertrophyen_US
dc.subjectPressure-Overloaden_US
dc.subjectInsulin-Resistanceen_US
dc.subjectGlucose-Oxidationen_US
dc.subjectSkeletal-Muscleen_US
dc.subjectIschemia-Reperfusionen_US
dc.titleHyponatremia and takotsubo syndrome: a review of pathogenetic and clinical implicationsen_US
dc.typeReview Articleen_US

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