The assessment of QT intervals in acute carbon monoxide poisoning

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dc.contributor.authorYelken, Birguel
dc.contributor.authorTanriverdi, Belkis
dc.contributor.authorCetinbas, Ferda
dc.contributor.authorMemis, Dilek
dc.contributor.authorSut, Necdet
dc.date.accessioned2024-06-12T10:55:41Z
dc.date.available2024-06-12T10:55:41Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Carbon monoxide (CO) poisoning is known to cause myocardial toxicity and life threatening arrhythmias. QT interval measured from electrocardiogram is an indirect measure of the heterogeneity of ventricular repolarization, which may contribute to ventricular arrhythmias. The purpose of the study was to investigate whether the carboxyhemoglobin (COHb) level may be related to the changes of QT, corrected QT (QTc), (IT dispersion (QTd), corrected Qtd (QTdc) and cardiac enzymes during carbon monoxide poisoning. Methods: We conducted an observational study; 104 patients who had been diagnosed with CO intoxication were included in the study. Measurement of QT, QTc, QTd and QTdc intervals were performed form electrocardiogram on admission, 24 and 48 hours after admission. Cardiac enzymes were measured at each time-point. The myocardial perfusion scan was determined in all patients I week after admission. Results: The QT interval level in 24h was significantly higher than admission level (p<0.001), additionally QTc interval levels in 24h and 48h were significantly lower than admission levels (p<0.001 and p<0.001, respectively). Carboxyhemoglobin level only significantly correlated with QT intervals (r=-0.288; p=0.019), troponin T (r=-0.297; p=0.007), and creatine kinase MB levels (r=0.262; p=0.020). As a result of ROC analysis the QT interval level was significantly powerful parameter to predict COHb (p=0.022). Conclusion: Our data indicate COHb level correlated with QT intervals and cardiac enzymes. Clinicians should possibly avoid QT prolonging drugs and carefully monitor the QT, QTc, QTdc intervals in patients at high risk of cardiac disability due to high levels of COHb after CO poisoning. (Anadolu Kardiyol Derg 2009; 9: 397-400)en_US
dc.identifier.endpage400en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue5en_US
dc.identifier.pmid19819791en_US
dc.identifier.scopus2-s2.0-70849120956en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage397en_US
dc.identifier.trdizinid94425en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/94425
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19507
dc.identifier.volume9en_US
dc.identifier.wosWOS:000271265900007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofAnatolian Journal Of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarbon Monoxide Poisoningen_US
dc.subjectCarboxyhemoglobinen_US
dc.subjectQT Intervalsen_US
dc.subjectPredictive Value Of Testsen_US
dc.subjectExercise Performanceen_US
dc.subjectDispersionen_US
dc.subjectExposureen_US
dc.titleThe assessment of QT intervals in acute carbon monoxide poisoningen_US
dc.typeArticleen_US

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