Formulation and evaluation of intimate wash containing manuka oil and salix bark extract

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dc.authoridGedik, Gülşah/0000-0003-4147-6729
dc.authorwosidGedik, Gülşah/GWC-6445-2022
dc.contributor.authorGedik, Gulsah
dc.date.accessioned2024-06-12T11:01:51Z
dc.date.available2024-06-12T11:01:51Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractMost of the feminine hygiene products sold in the market contain heavy chemicals that damage the mucosa. The well-designed intim formulation cleans without damage, supports the flora, protects against dryness, and maintenances of balanced microflora. For this purpose, we designed formulations made with natural raw materials such as manuka oil and Salix alba bark extract and investigated their irritation potential and effectiveness. A healthy vagina is dominated by Lactobacillus that produces lactic acid, resulting in a characteristic acidic environment (pH 34), as it correlates with vaginal health by inhibiting the growth of bacteria and may also play a part in local immune defense. This new manuka oil- salix bark extract containing wash formulation was specifically formulated to achieve a formulation pH of 4.6-4.8 to be compatible with the normal skin pH range and to help maintain vulvovaginal skin homeostasis and provide protection against harmful bacteria. The formulation we designed was used by volunteers for 4 weeks and was found suitable in terms of gentle clean, refreshing feeling, shooting the skin, smell and irritation properties. None of the volunteers have experienced any side effects during product application. Our study findings further support other studies that have found that women who use intim wash attitudes and perceptions about hygiene.en_US
dc.description.sponsorshipTan-Alize, Inc. Turkeyen_US
dc.description.sponsorshipThe author acknowledge the assistance of Seda Alaca to accomplish this manuscript. Financial support for this study was provided by Tan-Alize, Inc. Turkey.en_US
dc.identifier.doi10.29228/jrp.217
dc.identifier.endpage1260en_US
dc.identifier.issn2630-6344
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85137917604en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1252en_US
dc.identifier.trdizinid1125768en_US
dc.identifier.urihttps://doi.org/10.29228/jrp.217
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1125768
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21053
dc.identifier.volume26en_US
dc.identifier.wosWOS:000929825400015en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherMarmara Univen_US
dc.relation.ispartofJournal Of Research In Pharmacyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFeminine Washen_US
dc.subjectManuka Oilen_US
dc.subjectSalix Bark Extracten_US
dc.subjectFemale Intimate Hygieneen_US
dc.subjectVulvovaginalen_US
dc.subjectSodium Lauryl Sulfateen_US
dc.subjectContact-Dermatitisen_US
dc.subjectDefense-Mechanismsen_US
dc.subjectForearm Skinen_US
dc.subjectHygieneen_US
dc.subjectVulvaren_US
dc.subjectPhen_US
dc.titleFormulation and evaluation of intimate wash containing manuka oil and salix bark extracten_US
dc.typeArticleen_US

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