Comparison of Clinical Scoring Systems in the Management of Patients with Microangiopathic Hemolytic Anemia and Thrombocytopenia

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dc.authoridBaysal, Mehmet/0000-0001-7681-4623
dc.authoridKirkizlar, Onur/0000-0001-7523-8599
dc.authorwosidBaysal, Mehmet/E-9111-2018
dc.authorwosidKirkizlar, Onur/W-9594-2018
dc.contributor.authorBaysal, Mehmet
dc.contributor.authorUmit, Elif
dc.contributor.authorKirkizlar, Hakki Onur
dc.contributor.authorDemir, Ahmet Muzaffer
dc.date.accessioned2024-06-12T11:16:20Z
dc.date.available2024-06-12T11:16:20Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Several clinical scoring systems have been developed for the differential diagnosis of thrombotic microangiopathies (TMAs), all to predict and identify patients with ADAMTS13 deficiency and to start treatment as soon as possible. The first scoring system in this regard was the Bentley score, and the French score and PLASMIC score were developed afterwards. Materials and Methods: We aimed to evaluate the laboratory parameters and clinical features of patients who underwent plasma exchange with a prediagnosis of TTP at our clinic between 2007 and 2019 and whose ADAMTS13 enzyme levels were measured and to compare the findings with the scoring systems. Results: Data of 35 patients were evaluated. Twelve patients were evaluated as high risk according to all three scoring systems. A statistically significant relation was observed between all three scoring systems and ADAMTS13 levels. Conclusion: A moderate correlation was found between all three scoring systems and ADAMTS13 levels. We observed similar potential strength of all three scoring systems to predict TTP among other TMAs and we conclude that they are applicable in daily practice.en_US
dc.identifier.doi10.4274/tjh.galenos.2020.2020.0348
dc.identifier.endpage68en_US
dc.identifier.issn1300-7777
dc.identifier.issn1308-5263
dc.identifier.issue1en_US
dc.identifier.pmid33161686en_US
dc.identifier.scopus2-s2.0-85102267055en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage64en_US
dc.identifier.trdizinid485116en_US
dc.identifier.urihttps://doi.org/10.4274/tjh.galenos.2020.2020.0348
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/485116
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24284
dc.identifier.volume38en_US
dc.identifier.wosWOS:000623517300008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal Of Hematologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThrombotic Thrombocytopenic Purpuraen_US
dc.subjectPLASMIC Scoreen_US
dc.subjectThrombotic Microangiopathyen_US
dc.subjectFrench Scoreen_US
dc.subjectBentley Scoreen_US
dc.subjectSevere Adamts13 Deficiencyen_US
dc.subjectPlasmic Scoreen_US
dc.subjectPurpuraen_US
dc.subjectValidationen_US
dc.subjectRituximaben_US
dc.subjectRegistryen_US
dc.titleComparison of Clinical Scoring Systems in the Management of Patients with Microangiopathic Hemolytic Anemia and Thrombocytopeniaen_US
dc.typeArticleen_US

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