111In-Pentetreotide uptake in a follicular adenoma of the thyroid gland: A pitfall for111In-Pentetreotide scintigraphy
Küçük Resim Yok
Tarih
2006
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Ediciones Doyma, S.L.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A patient with suspicion of a neuroendocrine tumor of the pancreas underwent a somatostatin receptor scintigraphy using 111In- Pentetreotide. 111In-pentetreotide scintigraphy showed discrete uptake of the radiotracer in the head of the pancreas and focal uptake in the right upper thyroid lobe. Tracer uptake in the 24h planar image was higher compared to the 4h image, and decreased after 48 hours. Normal thyroid tissue and thyroid disorders, such as cancers, Hashimoto's thyroiditis, and adenomas often show increased uptake of 111In-pentetreotide resulting in a possible false positive interpretation in patients with neuroendocrine tumor. Adding a 48h planar image might contribute to the differential diagnosis between benign or malignant lesions, as in the present case where the uptake decreased in an adenoma after 48 hours.
Açıklama
Anahtar Kelimeler
111in-Pentetreotide; Thyroid Adenoma, Pentetreotide In 111; Pertechnetic Acid Tc 99m; Somatostatin Receptor; Chromogranin A; Diagnostic Agent; Drug Derivative; Indium; Pentetreotide; Radiopharmaceutical Agent; Serotonin; Somatostatin; Thyroglobulin; Tumor Protein; Adult; Article; Case Report; Drug Uptake; Human; Image Analysis; Male; Single Photon Emission Computer Tomography; Thyroid Adenoma; Thyroid Follicle Cell; Thyroid Gland; Thyroid Scintiscanning; Adenoma; Chemistry; Differential Diagnosis; Laboratory Diagnosis; Metabolism; Metastasis; Middle Aged; Neuroendocrine Tumor; Pancreas Tumor; Positron Emission Tomography; Scintiscanning; Thyroid Tumor; Adenoma; Chromogranin A; Diagnosis, Differential; False Positive Reactions; Humans; Indium Radioisotopes; Male; Middle Aged; Neoplasm Proteins; Neuroendocrine Tumors; Pancreatic Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Somatostatin; Serotonin; Somatostatin; Thyroglobulin; Thyroid Neoplasms
Kaynak
Revista Espanola de Medicina Nuclear
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
25
Sayı
5
