Egg and milk allergy in asthmatic children: Assessment by immulite allergy food panel, skin prick tests and double-blind placebo-controlled food challenges

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dc.authorscopusid55879012600
dc.authorscopusid57194735921
dc.authorscopusid6701376185
dc.authorscopusid6507222336
dc.authorscopusid6507137978
dc.contributor.authorYazicio?lu M.
dc.contributor.authorBaşpinar I.
dc.contributor.authorÖneş Ü.
dc.contributor.authorPala Ö.
dc.contributor.authorKiziler U.
dc.date.accessioned2024-06-12T10:28:02Z
dc.date.available2024-06-12T10:28:02Z
dc.date.issued1999
dc.description.abstractThere is a perception that asthmatic symptoms may be worsoned by ingestion of certain foods. This study aimed to investigate whether ingestion of cow's milk or egg might induce respiratory symptoms in asthmatic children. Fifty asthmatic children aged 1.5 to 6 years old, with positive Immulite Food Panel FP5 test results were included in the study. Fifty healthy children within the same age group were accepted as control group. Total serum IgE levels were measured and skin prick tests for food allergens including milk and egg were performed. All of the subjects underwent oral, double-blind, placebo-controlled challenge with fresh egg and cow's milk powder. Two medical histories were confirmed by double-blind, placebo-controlled challenge in 9 patients (22.2%). Skin prick tests were positive in 9 patients (18%) with milk and 18 patients (36%) with egg antigen. Two children experienced wheezing, one after ingesting milk and the other after egg challenge (4%). In the control group no positive reactions were seen with egg or milk challenges. Our findings confirm that food allergy can elicit asthma in children, but its incidence is low, even with major allergens such as egg and milk. History, specific IgE determinations and skin prick tests are not reliable in diagnosing food reactions. Since any diet can cause rapid deficiencies in infancy, diet restrictions must not be applied, without performing double-blind, placebo-controlled challenge.en_US
dc.identifier.endpage293en_US
dc.identifier.issn0301-0546
dc.identifier.issue6en_US
dc.identifier.pmid10611552en_US
dc.identifier.scopus2-s2.0-0033216867en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage287en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17054
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofAllergologia et Immunopathologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergy; Children's Asthma; Cow's Milk; Eggen_US
dc.subjectImmunoglobulin E; Animal; Article; Asthma; Blood; Child; Clinical Trial; Controlled Clinical Trial; Controlled Study; Double Blind Procedure; Egg; Female; Food Allergy; Human; Infant; Male; Milk; Preschool Child; Skin Test; Animals; Asthma; Child; Child, Preschool; Double-Blind Method; Eggs; Female; Food Hypersensitivity; Humans; Immunoglobulin E; Infant; Male; Milk; Skin Testsen_US
dc.titleEgg and milk allergy in asthmatic children: Assessment by immulite allergy food panel, skin prick tests and double-blind placebo-controlled food challengesen_US
dc.typeArticleen_US

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