Ovarian dysgerminoma associated with Pseudo-Meigs' syndrome and functioning ovarian stroma

dc.authoridOz Puyan, Fulya/0000-0001-5853-0109
dc.authoridPuyan, Fulya/0000-0001-5853-0109
dc.authorwosidOz Puyan, Fulya/A-7077-2018
dc.authorwosidPuyan, Fulya/V-7074-2019
dc.contributor.authorGücer, F
dc.contributor.authorOz-Puyan, F
dc.contributor.authorMülayim, N
dc.contributor.authorYüce, MA
dc.date.accessioned2024-06-12T10:59:56Z
dc.date.available2024-06-12T10:59:56Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground. We present the first case of an ovarian dysgerminoma complicated by pseudo-Meigs' syndrome. Furthermore, this is the fourth reported case of ovarian dysgerminoma with functioning ovarian stroma resulting elevated androgen levels preoperatively. Case. A 25-year-old white female was referred to our department for abdominal swelling and a rapidly enlarging abdominal mass. Chest X-ray showed massive right pleural effusion. Abdominopelvic CT scan showed a left adnexal solid mass and ascites. Preoperative abnormally elevated hormone levels were as follows: free testosterone 7.7 pg/mL, androstenodione 13.6 ng/mL, and cortisol 29.4 mu g/dL. Left salpingo-oophorectomy and wedge resection of the right ovary were performed. Final histopathological investigation of the left ovary was dysgerminoma associated with stromal luteinization. Conclusion. Dysgerminoma should be considered in the differential diagnosis in a young patient with a pelvic mass, ascites, and pleural effusion and preoperative counseling should be directed accordingly. In addition, dysgerminomas may be accompanied by ovarian stromal luteinization and steroid hormone production, which occasionally result in chemical or clinical hyperandrogenism. (c) 2005 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ygyno.2005.01.029
dc.identifier.endpage684en_US
dc.identifier.issn0090-8258
dc.identifier.issue2en_US
dc.identifier.pmid15863182en_US
dc.identifier.scopus2-s2.0-18144415037en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage681en_US
dc.identifier.urihttps://doi.org/10.1016/j.ygyno.2005.01.029
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20634
dc.identifier.volume97en_US
dc.identifier.wosWOS:000229231000061en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.ispartofGynecologic Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDysgerminomaen_US
dc.subjectPseudo-Meigs' Syndromeen_US
dc.subjectFunctioning Ovarian Stromaen_US
dc.subjectHyperandrogenismen_US
dc.subjectElevated Androgen Levelsen_US
dc.subjectTumoren_US
dc.subjectVirilizationen_US
dc.subjectPregnancyen_US
dc.titleOvarian dysgerminoma associated with Pseudo-Meigs' syndrome and functioning ovarian stromaen_US
dc.typeArticleen_US

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