Partial sleep deprivation therapy combined with sertraline induces more rapid improvements in quality of life items in major depressive disorder

Basit Öğe Kaydı
dc.authoridCaliyurt, Okan/0000-0002-0513-0619
dc.authorwosidCaliyurt, Okan/ABE-7339-2020
dc.contributor.authorCaliyurt, O
dc.contributor.authorGuducu, F
dc.date.accessioned2024-06-12T11:13:12Z
dc.date.available2024-06-12T11:13:12Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: Total or partial sleep deprivation was showed to have rapid antidepressive effects in depression. Sleep deprivation therapy in major depression constitutes insufficient antidepressive treatment response and depressive symptoms reoccur after one night of recovery. Combination of antidepressant medication with sleep deprivation therapy is generally indicated. These combination therapies were found more favorable overall therapeutic effect than antidepressive monotherapy. Methods: In this study, we examined the Quality of Life changes with the antidepressive therapy using partial sleep deprivation plus sertraline and sertraline monotherapy in patients with major depressive disorder. Thirteen patients received six partial sleep deprivation therapies in addition to sertraline, that sleep schedule in deprivation nights started at 11:00-12:00 p.m. to 03:00 a.m. and 11 patients treated with sertraline monotherapy as a control group. Quality of Life was evaluated with the WHOQOL-100, depression and the accompanying anxiety were also assessed at baseline and at the end of the 4th week. Results: Patients treated with combination therapy improved significantly and more rapidly. Rapid improvement in quality of life in major depressive disorder was showed in patients treated with combination of late partial sleep deprivation and sertraline. Limitations: Small sample size, the lack of placebo group and short duration of the study are the main limitations. Conclusions: In clinical practice, QOL improvement can be accelerated using combination of partial sleep deprivation with the sertraline therapy. (c) 2005 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.jad.2005.04.008
dc.identifier.endpage78en_US
dc.identifier.issn0165-0327
dc.identifier.issn1573-2517
dc.identifier.issue1en_US
dc.identifier.pmid15967511en_US
dc.identifier.scopus2-s2.0-23844523295en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage75en_US
dc.identifier.urihttps://doi.org/10.1016/j.jad.2005.04.008
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23463
dc.identifier.volume88en_US
dc.identifier.wosWOS:000231939200009en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal Of Affective Disordersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectQuality Of Lifeen_US
dc.subjectDepressionen_US
dc.subjectSleep Deprivation Therapyen_US
dc.subjectSertralineen_US
dc.subjectGlobal Burdenen_US
dc.subjectDouble-Blinden_US
dc.subjectAntidepressantsen_US
dc.subjectAmitriptylineen_US
dc.titlePartial sleep deprivation therapy combined with sertraline induces more rapid improvements in quality of life items in major depressive disorderen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu