The effects of short-term exposure to cadmium and copper on sialic acid in carp (Cyprinus carpio) tissues

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dc.authorscopusid6506312884
dc.authorscopusid18435963400
dc.authorscopusid21742310100
dc.contributor.authorAktaç T.
dc.contributor.authorBakar E.
dc.contributor.authorGüner U.
dc.date.accessioned2024-06-12T10:28:21Z
dc.date.available2024-06-12T10:28:21Z
dc.date.issued2010
dc.description.abstractThe aim of the present study was to determine the effects of cadmium and copper on the sialic acid levels of liver, gill, muscle and kidney of Cyprinus carpio following a 7-days exposure period at static conditions. Sialic acids (N-acetylneuraminic acids, SAs) are negatively charged monosaccharides that are common constituents in the oligosaccharides of vertebrates and some invertebrate species. Quantitative and qualitative differences in sialic acid are seen in health and disease, and at different stages of cell growth, differentiation, aging and malignant transformation. In this study, adult carps were exposed to 0.5, 2.5 and 5.0 ppm copper and 0.1, 0.5 and 1.0 ppm cadmium, and also for interaction of 0.5+0.1 ppm copper+cadmium concentrations under static conditions for one week. At the end of 7 days, all carps were dissected into their liver, gill, muscle and kidney tissues for evaluation of heavy metal accumulation (Cu and Cd), and for analyzing the sialic acid level. Accumulation of Cu and Cd in the tissues investigated was increased with the dose of the metal. Under in vitro conditions, Cu, which is a useful ion for normal tissue function, has an antagonistic effect with sialic acid in the tissue. In contrast, Cd, which is not involved in any physiological function, has a synergistic effect with sialic acid. According to the results of this study, it could be suggested that tissue sialic acid interacts with metal ions under in vitro conditions. On the other hand, it is also possible that these results are due to direct effects of the metal ions on sialic acid metabolism. © by PSP.en_US
dc.identifier.endpage437en_US
dc.identifier.issn1018-4619
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-77952123799en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage432en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17204
dc.identifier.volume19en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAccumulation; Cadmium; Carp; Copper; Cyprinus Carpio; Interaction; Sialic Aciden_US
dc.subjectBioaccumulation; Cadmium; Copper; Cyprinid; Dose-Response Relationship; Experimental Study; Monosaccharide; Physiological Response; Cyprinidae; Cyprinus Carpio; Invertebrata; Vertebrataen_US
dc.titleThe effects of short-term exposure to cadmium and copper on sialic acid in carp (Cyprinus carpio) tissuesen_US
dc.typeArticleen_US

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