Systemic Inflammation and Arrhythmogenesis: A Review of Mechanistic and Clinical Perspectives

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dc.contributor.authorYalta, Tulin
dc.contributor.authorYalta, Kenan
dc.date.accessioned2024-06-12T11:15:56Z
dc.date.available2024-06-12T11:15:56Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIn the recent decades, systemic inflammation, as a clinical phenomenon, has been the focus of extensive research particularly with regard to its potential association with a variety of cardiovascular diseases including atherogenesis and acute coronary syndromes. Within this context, there also exists a potential link between systemic inflammation and cardiac arrhythmogenesis in various aspects. Accordingly, systemic inflammation response as measured with inflammation markers (cytokines, etc) has been investigated in the setting of well-known cardiac arrhythmias including atrial fibrillation and ventricular tachycardia. Based on current literature, clinical utility of these markers might potentially yield important prognostic implications in the setting of certain arrhythmogenic conditions. On the other hand, there exists limited data regarding therapeutic implications including clinical benefit of primary anti-inflammatory agents (corticosteroids, colchicine, etc) in the setting of arrhythmia management. The present review primarily aims to discuss potential triggers and fundamental mechanisms of inflammation-related arrhythmias along with a particular emphasis on clinical implications of systemic inflammation in the setting of cardiac arrhythmogenesis.en_US
dc.identifier.doi10.1177/0003319717709380
dc.identifier.endpage296en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue4en_US
dc.identifier.pmid28539056en_US
dc.identifier.scopus2-s2.0-85032286896en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage288en_US
dc.identifier.urihttps://doi.org/10.1177/0003319717709380
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24131
dc.identifier.volume69en_US
dc.identifier.wosWOS:000429752100003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSystemic Inflammationen_US
dc.subjectArrhythmogenesisen_US
dc.subjectPotential Triggersen_US
dc.subjectPotential Mechanismsen_US
dc.subjectClinical Implicationsen_US
dc.subjectTumor-Necrosis-Factoren_US
dc.subjectAcute Myocardial-Infarctionen_US
dc.subjectAtrial-Fibrillation Recurrenceen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectFactor-Alphaen_US
dc.subjectRheumatoid-Arthritisen_US
dc.subjectPostpericardiotomy-Syndromeen_US
dc.subjectCardiovascular-Diseaseen_US
dc.subjectThrombin Generationen_US
dc.subjectCatheter Ablationen_US
dc.titleSystemic Inflammation and Arrhythmogenesis: A Review of Mechanistic and Clinical Perspectivesen_US
dc.typeReview Articleen_US

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