Synthesis and Characterization of New Binaphthyl-Linked Phenanthroline-, Bipyridine-, or Pyridine-Derived Ligands, and the Study of Their Cytotoxic Activity
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-V C H Verlag Gmbh
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In the present work, we describe the synthesis and characterization of five new versatile acyclic or macrocyclic ligands containing binaphtyl-linked pyridine, bipyridine, or phenanthroline groups in their framework (see Schemes 1-4). The structures of the ligands were elucidated on the basis of elemental analyses. 1R, (1)H-NMR, (13)C-NMR, and FAB mass spectra. The cytotoxicity of these compounds was tested in vitro by using the tetrazolium salt reduction (MTT) assay on A549 (human lung carcinoma epithelial like) cells. All Of the tested compounds induced time- and concentration-dependent cytotoxic effect.
Açıklama
Anahtar Kelimeler
Complex, Binol, Coordination, Cadmium(Ii), Chemistry, Dna
Kaynak
Helvetica Chimica Acta
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
91
Sayı
11
