Do you have restless leg syndrome? I understood from your eyes

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dc.authoridsolmaz, volkan/0000-0002-9045-2347
dc.authorwosidOzal, Sadık Altan/B-5123-2019
dc.contributor.authorOzlece, Hatice Kose
dc.contributor.authorSolmaz, Volkan
dc.contributor.authorOzal, Sadik Altan
dc.contributor.authorCelik, Yahya
dc.date.accessioned2024-06-12T11:13:37Z
dc.date.available2024-06-12T11:13:37Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose According to many studies in the literature, there is a strong association between restless leg syndrome and dopaminergic dysfunction. Dopamine is also the major catecholamine in the retina and is also a possible transmitter of the amacrine and interplexiform cells. The aim of this study is to investigate the possible association between RLS and retinal thickness. Methods In this study, we included 33 patients who were diagnosed with idiopathic RLS according to the International RLS Study Group criteria and 31 healthy subjects. All the patients and controls underwent routine ophthalmologic examination and had spectral-domain optical coherence tomography (OCT) performed. We compared the retinal thickness of the patients and control subjects. Results In the RLS group, foveal thickness was thinner then controls. Also, only inferior, superior, and temporal quadrant retina nerve fiber layer (RNFL) thickness were significantly thinner in the RLS group. The parafoveal ganglion cell complex (GCC) in the superior temporal, inferior temporal, inferior nasal quadrant, and perifoveal superior nasal thickness was also significantly thinner in the patient group. Pearson correlation analyses showed that there were statistically significant negative correlations between disease duration and macular GCC and RNFL thickness. Negative correlations were also detected between parafoveal superior, temporal, inferior and nasal macular thickness, parafoveal superior nasal, inferior temporal GCC thickness, and perifoveal superior nasal GCC thickness and disease duration. Conclusion According to our results; most retinal layers are thinner in RLS patients, so it can be considered that OCT has a predictive value for progression of RLS.en_US
dc.identifier.doi10.1007/s11325-018-1740-5
dc.identifier.endpage557en_US
dc.identifier.issn1520-9512
dc.identifier.issn1522-1709
dc.identifier.issue2en_US
dc.identifier.pmid30341586en_US
dc.identifier.scopus2-s2.0-85055705380en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage551en_US
dc.identifier.urihttps://doi.org/10.1007/s11325-018-1740-5
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23609
dc.identifier.volume23en_US
dc.identifier.wosWOS:000468613100017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofSleep And Breathingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRestless Leg Syndromeen_US
dc.subjectOCTen_US
dc.subjectRetinal Thicknessen_US
dc.subjectOptical Coherence Tomographyen_US
dc.subjectNerve-Fiber Layeren_US
dc.subjectParkinson Diseaseen_US
dc.subjectRetinal Changesen_US
dc.subjectD2 Receptorsen_US
dc.subjectDopamineen_US
dc.subjectMovementsen_US
dc.subjectSleepen_US
dc.subjectHeaden_US
dc.titleDo you have restless leg syndrome? I understood from your eyesen_US
dc.typeArticleen_US

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