Evaluation of Macular, Ganglion Cell Complex and Retinal Nerve Fibre Layer Thickness Changes in Preperimetric Glaucomatous Eyes

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dc.contributor.authorSakallıoğlu, Ahmet Kürşad
dc.contributor.authorGürlü, Vuslat
dc.contributor.authorGarip, Rüveyde
dc.contributor.authorGüçlü, Hande
dc.date.accessioned2024-06-12T10:05:18Z
dc.date.available2024-06-12T10:05:18Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: To investigate macular thickness (MT), ganglion cell complex (GCC), and retinal nerve fiber layer (RNFL) thickness changes in preperimetric glaucoma patients. Materials and Methods: In the present study 105 eyes of 75 patients were investigated. Of these patients, 56 eyes of 45 patients who were diagnosed as preperimetric glaucoma are taken as a study group and 49 eyes of 30 cases without any ocular pathology are taken as the control group. The mean values of central MT, parafoveal MT, perifoveal MT, parafoveal GCC thickness, and perifoveal GCC thickness evaluations using optical coherence tomography (OCT) were compared between the two groups. Peripapillary RNFL measurements; the mean values of the total, superior hemi-central, inferior hemi-central, superior, inferior, nasal, and temporal quadrants, and twelve sectors were compared between the two groups. Results: In the study group, perifoveal GCC thickness was significantly thinner in the superonasal, superotemporal, inferonasal, and inferotemporal quadrants compared to the control group. Peripapillary RNFL thickness was significantly thinner in the study group in total, superior hemi-central, inferior hemi-central, superior, inferior, nasal, temporal, and hour 1,2,3,4,5,7,8,9 quadrants. No significant difference was detected between the two groups in other measurements (p>0.05). Conclusion: However both macular and peripapillary cellular losses have been initiated in cases with preperimetric glaucoma, this loss can not be detected by standard automated perimetry. As a result, perifoveal GCC and peripapillary RNFL measurements by OCT in patients with preperimetric glaucoma are very helpful for diagnosing suspicious cases.en_US
dc.identifier.doi10.37844/glau.cat.2022.17.27
dc.identifier.endpage172en_US
dc.identifier.issn1305-9173
dc.identifier.issn2717-7157
dc.identifier.issue4en_US
dc.identifier.startpage166en_US
dc.identifier.trdizinid1174971en_US]
dc.identifier.urihttps://doi.org/10.37844/glau.cat.2022.17.27
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1174971
dc.identifier.urihttps://hdl.handle.net/20.500.14551/13360
dc.identifier.volume17en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofGlokom Katarakten_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of Macular, Ganglion Cell Complex and Retinal Nerve Fibre Layer Thickness Changes in Preperimetric Glaucomatous Eyesen_US
dc.typeArticleen_US

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