Electroclinical patterns in patients with nonconvulsive status epilepticus: Etiology, treatment, and outcome

Basit Öğe Kaydı
dc.authorscopusid56690614100
dc.authorscopusid57216783881
dc.authorscopusid56646520000
dc.authorscopusid57220161298
dc.authorscopusid24068634800
dc.contributor.authorBaysal-Kirac L.
dc.contributor.authorCakar M.M.
dc.contributor.authorAltiokka-Uzun G.
dc.contributor.authorGuncan Z.
dc.contributor.authorGuldiken B.
dc.date.accessioned2024-06-12T10:25:08Z
dc.date.available2024-06-12T10:25:08Z
dc.date.issued2021
dc.description.abstractIntroduction: This study investigated the clinical and electroencephalography (EEG) features and prognostic factors of patients with nonconvulsive status epilepticus (NCSE). Materials and methods: We retrospectively reviewed the clinical files and EEG data of 45 (28 females, mean age 54 ± 22.6 years) consecutive patients with NCSE over a five-year period. An EEG interpreter who was blinded to the clinical findings evaluated the EEGs according to the Salzburg Consensus Criteria (SCC) for NCSE. Patient demographics, etiology, neuroimaging and laboratory data, EEG features, treatment, and outcome measures were analyzed. Results: The most common etiology for NCSE was acute symptomatic etiologies (57.8%) and cerebrovascular disease (48.9%). The majority (68.9%) of the patients presented with new-onset status epilepticus (SE). NCSE was refractory to treatment in 31.1% of patients. The most common status pattern consisted of rhythmic delta/theta activity in 62.3% of EEGs. Twenty-five status patterns on the EEGs were classified as definite, 30 as possible, and six as no NCSE according to the SCC. The in-hospital mortality rate was high (33.3%) showing an association with potentially fatal etiology, refractory SE, treatment with continuous I.V. anesthetics and also the presence of multiple status patterns and nonreactivity in EEGs (p < 0.05). Conclusions: The SCC for NCSE have high diagnostic accuracy but do not affect prognosis. Potentially fatal etiology, multiple status patterns on EEG and non-reactive EEGs may carry significantly greater risk for short-term mortality. © 2020 Elsevier Inc.en_US
dc.identifier.doi10.1016/j.yebeh.2020.107611
dc.identifier.issn1525-5050
dc.identifier.pmid33272894en_US
dc.identifier.scopus2-s2.0-85097102984en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1016/j.yebeh.2020.107611
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16183
dc.identifier.volume114en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAcademic Press Inc.en_US
dc.relation.ispartofEpilepsy and Behavioren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEeg; Epilepsy; Nonconvulsive Status Epilepticus; Salzburg Consensus Criteriaen_US
dc.subjectAnticonvulsive Agent; Diazepam; Levetiracetam; Phenytoin; Adult; Article; Cerebrovascular Disease; Clinical Article; Computer Assisted Tomography; Controlled Study; Demography; Diagnostic Accuracy; Electroencephalogram; Electroencephalography; Epileptic State; Female; Human; Laboratory Test; Male; Middle Aged; Mortality Rate; Neuroimaging; Outcome Assessment; Prognosis; Retrospective Study; Tonic Clonic Seizure; Treatment Outcome; Aged; Cerebrovascular Disease; Epileptic State; Adult; Aged; Cerebrovascular Disorders; Electroencephalography; Female; Humans; Middle Aged; Prognosis; Retrospective Studies; Status Epilepticusen_US
dc.titleElectroclinical patterns in patients with nonconvulsive status epilepticus: Etiology, treatment, and outcomeen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu