The effects of dexmedetomidine on shivering and the change of the body temperature under general anesthesia and epidural block
Küçük Resim Yok
Tarih
2007
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Pharmacological agents are choosen for the treatment of postoperative shivering. Clinical studies are going on to find perfect agent with low side effects. In our study we aimed to investigate the effects of dexmedetomidine infusion on postoperative shivering and the change of the body temperature during general anesthesia and epidural ansthesia. Patients were randomly divided into two goups; Group I (n=50) receiving general anesthesia and Group II (n=50) epidural anesthesia. After induction of general anesthesia Group I was divided into two subgroups. Similarly Group II was divided into two subgroups when the block reached to the T 6 level. Group IA and Group IIA were administered saline solution, where Group IB (n=25) and IIB received 2 ?g mL -1 prepared dexmedetomidine solution, 0.25 mL kg -1 hr -1 dexmedetomidine infusion was administered for 10 minutes subsequently 0.1 mL kg -1 hr -1 infusion for maintenance. The heart rate (HR), systolic arteriel pressure (SAP), diastolic arteriel pressure (DAP), peripheral oxygen saturation (SpO 2) tympanic membrane temperature of all patients were recorded after induction or block and at 30, 60, 90 th minutes. In Group II sedation scores were also recorded. HR, SAP, DAP, SpO 2 tympanic, membrane temperature, shivering scores, sedation scores were recorded post operative at 15, 30, 60 th minutes. The patients who had shivering score more than 3 were administered intravenous 25 mg meperidin. The dosage and times of meperidin given were recorded. Postoperative 60 th minute the patients who have Aldtrete score of 9 were externed to their services. In Group IA compared group IB intraoperative 30 th minute and 90 th minute HR and DAP values and intraoperative 30, 60, 90 th minutes tympanic membrane values were found lower (p<0.05). No statistically significant differences were determined between the postoperative groups with respect to hemodynamic values, tympanic membrane temperature, sedation levels, shivering scores, nause and vomiting, mepcrdin consumption and side effects. VAS was found significantly higher in GroupI than GroupII (p<0.05). The mean ages of patients with shivering score ?3 were lower than the ones with shivering score <3, but the sexualities were found similiar. In conclusion, we found that the infusion of dexmedetomidine decreased the body temperature and hemodynamic values with the dose we used intraoperatively on the cases under general anesthesia, but on the other hand we didn't observe these effects under epidural anesthesia.
Açıklama
Anahtar Kelimeler
Anesthesia; Body Temperature Regulation; Dexmedetomidine; Shivering; Tympanic Membrane Temperature
Kaynak
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
35
Sayı
4
