Role of Chronobiology as a Transdisciplinary Field of Research: Its Applications in Treating Mood Disorders

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dc.contributor.authorÇalıyurt, Okan
dc.date.accessioned2021-11-20T10:10:04Z
dc.date.available2021-11-20T10:10:04Z
dc.date.issued2017
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Ruh Sağlığı ve Hastalıkları Anabilim Dalıen_US
dc.description.abstractChronobiology is a field that studies the effects of time on biological systems. Periodicity is of particular interest. The master biological clock in the suprachiasmatic nucleus controls daily rhythms of core body temperature, rest-activity cycle, physiological and behavioral functions, psychomotor functions and mood in humans. The clock genes are involved in the generation of the circadian rhythms and the biological clock is synchronized to solar day by direct photic inputs. Various circadian rhythm abnormalities have been demonstrated in mood disorders such as unipolar depression, bipolar depression and seasonal affective disorder. Hypotheses involving circadian rhythm abnormalities related to the etiology of mood disorders have been raised. The resulting circadian rhythm changes can be measured and evaluated that these techniques can be used to identify subtypes of mood disorders associated with circadian rhythm changes. The data obtained from chronobiological studies reveal methods that manipulate circadian rhythms. The effects of lightand melatonin on circadian rhythms are determined by these studies. Chronobiological research has been applied to the psychiatric clinic and light therapy has been used as a chronotherapeutic in the treatment of mood disorders. On the other hand, chronotherapeutic approaches with effects on circadian rhythms such as sleep deprivation therapy have been used in the treatment of mood disorders too. As a good example of translational psychiatry, chronobiological studies have been projected in the psychiatry clinic. It may be possible, the data obtained from the basic sciences are used in the diagnosis of mood disorders and in the treatment of psychiatric disorders as chronotherapeutic techniques. Developments in the field of chronobiology and data obtained from chronotherapeutics may enable the development of evidence-based diagnosis and treatment in psychiatryen_US
dc.identifier.doi10.4274/balkanmedj.2017.1280en_US
dc.identifier.endpage521en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue6en_US
dc.identifier.pmid29072179en_US
dc.identifier.scopus2-s2.0-85038251172en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage514en_US
dc.identifier.trdizinid268515en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpZNE5URTFOUT09
dc.identifier.urihttps://hdl.handle.net/20.500.14551/5492
dc.identifier.volume34en_US
dc.identifier.wosWOS:000423241000006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÇalıyurt, Okan
dc.language.isoenen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240608_ID_Qen_US
dc.subjectCerrahien_US
dc.titleRole of Chronobiology as a Transdisciplinary Field of Research: Its Applications in Treating Mood Disordersen_US
dc.typeArticleen_US

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