Comparison of maternal and neonatal effects of sevoflurane, isoflurane and helothane in elective cesarean section
Küçük Resim Yok
Tarih
1999
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, we aimed to compare the maternal and neonatal effects of sevoflurane, isoflurane and halothane in elective cesarean section. The study was performed in 90 pregnants (Group A) in term undergoing elective cesarean section and their 90 neonates (Gr B). The pregnants and neonates were divided in to three equal (n: 30) subgroups according to the administration of volatile anaesthetics: Gr 1;1 % sevoflurane, Gr II; 0.75 % isoflurane, Gr III; 0,5 % halothane. In the Gr A, before and after intubation heart rate, systolic and diastolic arterial pressures were recorded. Induction-delivery (I-D) and uterine incision-delivery (U-D) intervals; before intubation and after clamping of umblical cord, arterial blood gas tensions; spontaneous eye opening and tracheal extubation times were recorded. In the Gr B, umbilical artery and vein (U-A, U-V) blood gas tensions and acid-base values were recorded. Apgar scores were evaluated at the 1st, 5th and 10th min. The relation between I-D, U-D intervals and U-A and U-V pH vahtes and Apgar scores at 1st minute was evaluated. In the Group A, maternal parameters values were found similar in three subgroups (p>0.05). In the Gr B, U-A and U-V blood gas tensions and Apgar scores at 1st, 5th and 10th min were not significant between three groups with the exception of the comparison of Gr I and III at the 10th min values (p=0.011). The relation between I-D intervals and U-A pH values and Apgar scores at 1st min was found to be insignificant in three subgroups. Although the relation between U-D intervals in Gr I, U-V pH values in Gr III and Apgar scores at 1st minute was found to be significantly (p=0.006, 0.032). As a result, we conclude that each of the three volatile agents have minimum adverse effects on pregnants and neonates and sevoflurane seem to be an acceptable alternative to isoflurane and halothane for elective cesarean section.
Açıklama
Anahtar Kelimeler
Cesarean Section; Halothane; Isoflurane; Maternal-Neonatal Effects; Sevoflurane, Halothane; Isoflurane; Sevoflurane; Apgar Score; Article; Blood Gas Tension; Blood Ph; Blood Pressure; Cesarean Section; Female; Human; Major Clinical Study; Newborn; Obstetric Anesthesia; Oxygen Saturation
Kaynak
Turk Anesteziyoloji ve Reanimasyon
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
27
Sayı
10
