The effect of normal and low hematocrit levels on cognitive functions during cardiopulmonary bypass
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The frequency of postoperative cognitive disfunction (PCD) is 60-80 % in the early postoperative period. The frequency of PCD after coronary artery bypass grefting (CABG) surgery can change associated with a lot of factors such as using or not using cardiopulmonary bypass pump, cerebral embolism, systemic inflamation, the body temparature and cerebral hemodynami. The aim of our study is to examine the effects of low hematocrit levels (< 20 %) on mini mental state test (MMST) during cardiopulmonary bypass. Patients between the age of 50-77 years, in the ASA I-II group who would undergo CABG surgery were included to the study. They didn't have any neurological and neuropsychiatrical problems and were not using any psychotic agents. The MMST was performed to the patients who would undergo CABG surgery, on the day before the operation and on the postopertive sixth day. After the induction of anesthesia 1-2 units whole blood was collected from the patients. The MMST values of the subjects who had the hematocrit levels of 15-19 % (Group I, n=100) and the hematocrit levels of 20-25 % (Group II, n=100) during the cardiopulmonary bypass were compared. Demografic features, durations of the operation, x-clamp and intubation, the length of intensive care unit stays and the hematocrit levels at the time of MMST were similar in all subjects. On the postoperative sixth day, there was no statistical difference in the MMST values of the subjects who had low hematocrit levels during cardiopulmonary bypass. In conclusion, we think that the low hematocrit levels during cardiopulmonary bypass have no egative effects on MMST however using different tests may change the outcome.
Açıklama
Anahtar Kelimeler
Cardiopulmonary Bypass; Cognitive Impairment; Coronary Artery Bypass Grafting Surgery; Hematocrit, Neuroleptic Agent; Adult; Aged; Anesthesia Induction; Article; Blood; Blood Sampling; Body Temperature; Cardiopulmonary Bypass; Cognition; Cognitive Defect; Controlled Study; Coronary Artery Bypass Surgery; Demography; Diagnostic Value; Female; Hematocrit; Hemodynamics; Human; Intensive Care Unit; Intubation; Length Of Stay; Major Clinical Study; Male; Mini Mental State Examination; Neurologic Examination; Operation Duration; Outcome Assessment; Patch Clamp; Postoperative Care; Preoperative Evaluation
Kaynak
Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
14
Sayı
4
