Effect of collateral circulation on healing of small intestinal anastomosis in rabbits

Basit Öğe Kaydı
dc.contributor.authorAltan, A
dc.contributor.authorCakir, E
dc.contributor.authorKayapinar, R
dc.contributor.authorGega, F
dc.date.accessioned2024-06-12T11:08:23Z
dc.date.available2024-06-12T11:08:23Z
dc.date.issued1997
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground/Aims: In patients who have acute superior mesenteric artery occlusion and clearly gangrenous intestines, resection and anastomosis have been advised as the only surgical procedure. Distal and proximal bowel segments adjacent to this necrotic part have collateral blood supply although they have normal macroscopic appearance. After resection of necrotic segment, there will be a lore flow at the anastomosis due to collateral circulation and the healing may therefore be impaired. Methodology: This situation was investigated in rabbits creating unilateral collateral circulation at the small bowel anastomosis. Bursting pressure, tissue hydroxyproline concentration and bursting sites were determined on days 4, 8, and 12. Findings were compared with the those of normal anastomosis. Results: There was significantly decreased mean bursting pressure(106+/-40.3 mmHg) in unilateral collateral circulation group as compared with the that of control group (158+/-26.6 mmHg) on day 8 (p<0.05). On the same day mean hydroxyproline concentration of this group was also lower(7.06+/-0.5 mg/g tissue) than the value of control group(7.69+/-0.4 mg/g tissue), with the statistical significance on the border line(p=0.05). The low values of these two parameters reached normal levels on day 12, Bursting sites Lc)ere mostly on the anastomotic line in unilateral collateral circulation group, while they were mostly on the bowel wall in the control group on day 8. Conclusion: These findings suggest an insufficient healing process in the bowel anastomosis with unilateral collateral circulation on day 8 in rabbits.en_US
dc.identifier.endpage1050en_US
dc.identifier.issn0172-6390
dc.identifier.issue16en_US
dc.identifier.pmid9261597en_US
dc.identifier.startpage1046en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22400
dc.identifier.volume44en_US
dc.identifier.wosWOS:A1997XP15900020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherH G E Update Medical Publishing S Aen_US
dc.relation.ispartofHepato-Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMesenteric Vascular Occlusionen_US
dc.subjectBlood Supplyen_US
dc.subjectCollateral Circulationen_US
dc.subjectIschemiaen_US
dc.subjectFlowen_US
dc.subjectRatsen_US
dc.titleEffect of collateral circulation on healing of small intestinal anastomosis in rabbitsen_US
dc.typeArticleen_US

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