Evaluation of Overactive Bladder in Male Antidepressant Users: A Prospective Study

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dc.authoridAksoy, Dürdane/0000-0003-1981-084X
dc.authoridsolmaz, volkan/0000-0002-9045-2347
dc.authorwosidAksoy, Dürdane/B-7835-2017
dc.contributor.authorSolmaz, Volkan
dc.contributor.authorAlbayrak, Sebahattin
dc.contributor.authorTekatas, Arslan
dc.contributor.authorAksoy, Durdane
dc.contributor.authorGencten, Yusuf
dc.contributor.authorInanir, Sema
dc.contributor.authorErdemir, Fikret
dc.date.accessioned2024-06-12T11:16:58Z
dc.date.available2024-06-12T11:16:58Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: In this study, we investigated overactive bladder (OAB) functions in male patients who used antidepressant drugs (ADs) that were previously examined in female patients, based on conflicting data in literature regarding the effects of AD on OAB and the differences between male and female urinary system physiologies (anatomical and hormonal). Methods: The study included 202 male patients (a control group of 90 healthy subjects, and an experimental group of 112 patients taking ADs for different disorders). All the patients completed the overactive bladder-validated 8 (OAB-V8) questionnaire, the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), and the Beck Depression Inventory (BDS). Results: The OAB-V8, ICIQ-SF, and BDS scores for the antidepressant users were significantly higher than those of the control group. The highest prevalence of OAB symptoms was observed in patients taking venlafaxine (68.2%), and the lowest prevalence was in patients taking sertraline (28.0%). Moreover, the frequency of OAB between the antidepressant groups was statistically significant. The univariate logistic regression analyses showed a significant relationship between the presence of OAB, antidepressant usage, BDS score, and the age of a patient. In the multivariate logistic regression analyses, the association between the presence of OAB and antidepressant usage was statistically significant. Conclusions: The present study showed that the incidence of OAB and the severity of OAB symptoms increased in males using antidepressants for various disorders. This may have been due to unique pharmacological effects, on a molecular or individual level, of serotonin-norepinephrine reuptake inhibitors.en_US
dc.identifier.doi10.5213/inj.1732652.326
dc.identifier.endpage67en_US
dc.identifier.issn2093-4777
dc.identifier.issn2093-6931
dc.identifier.issue1en_US
dc.identifier.pmid28361516en_US
dc.identifier.scopus2-s2.0-85016312419en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage62en_US
dc.identifier.urihttps://doi.org/10.5213/inj.1732652.326
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24522
dc.identifier.volume21en_US
dc.identifier.wosWOS:000397737200010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Continence Socen_US
dc.relation.ispartofInternational Neurourology Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUrinary Bladderen_US
dc.subjectOveractiveen_US
dc.subjectAntidepressive Agentsen_US
dc.subjectValidation Studiesen_US
dc.subjectUrinary-Incontinenceen_US
dc.subjectDepressionen_US
dc.subjectSymptomsen_US
dc.subjectWomenen_US
dc.subjectAnxietyen_US
dc.subjectDrugen_US
dc.subjectPrevalenceen_US
dc.subjectDisordersen_US
dc.subjectNocturiaen_US
dc.titleEvaluation of Overactive Bladder in Male Antidepressant Users: A Prospective Studyen_US
dc.typeArticleen_US

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